H-Tyr(3-I)-OH( 3-Iodo-L-tyrosine )

Catalog No. M20288 CAS No. 70-78-0

H-Tyr(3-I)-OH is an inhibitor of tyrosine hydroxylase (Ki = 0.39 M) and an intermediate in the synthesis of thyroid hormones.

Purity : >98% (HPLC)

COA

Datasheet

HNMR

HPLC

MSDS

Handing Instructions

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Biological Information

Product Name

H-Tyr(3-I)-OH
Note

Research use only, not for human use.
Brief Description

H-Tyr(3-I)-OH is an inhibitor of tyrosine hydroxylase (Ki = 0.39 M) and an intermediate in the synthesis of thyroid hormones.
Description

H-Tyr(3-I)-OH is an inhibitor of tyrosine hydroxylase (Ki = 0.39 M) and an intermediate in the synthesis of thyroid hormones.
In Vitro

H-Tyr(3-I)-OH (3-iodo-L-tyrosine) is as effective inhibitor of tyrosine hydroxylase. At a concentration of 100μM 3-iodo-L-tyrosine inhibits the enzymatic activity 100% and at a concentration of 10μM it inhibits 60-70%.
In Vivo

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Synonyms

3-Iodo-L-tyrosine
Pathway

Proteasome/Ubiquitin
Target

Endogenous Metabolite
Recptor

Human Endogenous Metabolite
Research Area

——
Indication

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Chemical Information

CAS Number

70-78-0
Formula Weight

307.09
Molecular Formula

C9H10INO3
Purity

>98% (HPLC)
Solubility

H2O:6.25 mg/mL (20.35 mM) DMSO:1 mg/mL
SMILES

N[C@@H](Cc1ccc(O)c(I)c1)C(O)=O
Chemical Name

——

Shipping & Storage Information

Storage

(-20℃)
Shipping

With Ice Pack
Stability

≥ 2 years

Reference

1.Fernández-Espejo Emilio Cristian B H . Excess amounts of 3-iodo-L-tyrosine induce Parkinson-like features in experimental approaches of Parkinsonism[J]. NeuroToxicology 2018:S0161813X18301980-.

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