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H-Tyr(3-I)-OH
CAS No. 70-78-0
H-Tyr(3-I)-OH( 3-Iodo-L-tyrosine )
Catalog No. M20288 CAS No. 70-78-0
H-Tyr(3-I)-OH is an inhibitor of tyrosine hydroxylase (Ki = 0.39 M) and an intermediate in the synthesis of thyroid hormones.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 100MG | Get Quote | In Stock |
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| 200MG | Get Quote | In Stock |
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| 500MG | Get Quote | In Stock |
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| 1G | 27 | In Stock |
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Biological Information
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Product NameH-Tyr(3-I)-OH
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NoteResearch use only, not for human use.
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Brief DescriptionH-Tyr(3-I)-OH is an inhibitor of tyrosine hydroxylase (Ki = 0.39 M) and an intermediate in the synthesis of thyroid hormones.
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DescriptionH-Tyr(3-I)-OH is an inhibitor of tyrosine hydroxylase (Ki = 0.39 M) and an intermediate in the synthesis of thyroid hormones.
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In VitroH-Tyr(3-I)-OH (3-iodo-L-tyrosine) is as effective inhibitor of tyrosine hydroxylase. At a concentration of 100μM 3-iodo-L-tyrosine inhibits the enzymatic activity 100% and at a concentration of 10μM it inhibits 60-70%.
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In Vivo——
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Synonyms3-Iodo-L-tyrosine
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PathwayProteasome/Ubiquitin
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TargetEndogenous Metabolite
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RecptorHuman Endogenous Metabolite
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Research Area——
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Indication——
Chemical Information
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CAS Number70-78-0
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Formula Weight307.09
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Molecular FormulaC9H10INO3
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Purity>98% (HPLC)
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SolubilityH2O:6.25 mg/mL (20.35 mM) DMSO:1 mg/mL
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SMILESN[C@@H](Cc1ccc(O)c(I)c1)C(O)=O
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1.Fernández-Espejo Emilio Cristian B H . Excess amounts of 3-iodo-L-tyrosine induce Parkinson-like features in experimental approaches of Parkinsonism[J]. NeuroToxicology 2018:S0161813X18301980-.
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