Phenyl-ac-Gly-OH

CAS No. 500-98-1

Phenyl-ac-Gly-OH( Phenylacetyl glycine | Phenaceturic acid )

Catalog No. M20043 CAS No. 500-98-1

Phenylacetylglycine is an acyl glycine. Acyl glycines are normally minor metabolites of fatty acids. The presence of phenylacetylglycine in urine has been confirmed for dogs rats and mice. However the presence of this compound in human urine is controversial. GC-MS studies have not found this compound while NMR studies claimed to have identified it.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
1 mL x 10 mM in DMSO 28 In Stock
100MG 51 In Stock
200MG Get Quote In Stock
500MG Get Quote In Stock
1G Get Quote In Stock

Biological Information

  • Product Name
    Phenyl-ac-Gly-OH
  • Note
    Research use only, not for human use.
  • Brief Description
    Phenylacetylglycine is an acyl glycine. Acyl glycines are normally minor metabolites of fatty acids. The presence of phenylacetylglycine in urine has been confirmed for dogs rats and mice. However the presence of this compound in human urine is controversial. GC-MS studies have not found this compound while NMR studies claimed to have identified it.
  • Description
    Phenylacetylglycine is an acyl glycine. Acyl glycines are normally minor metabolites of fatty acids. The presence of phenylacetylglycine in urine has been confirmed for dogs rats and mice. However the presence of this compound in human urine is controversial. GC-MS studies have not found this compound while NMR studies claimed to have identified it.
  • In Vitro
    Apoptosis Analysis Cell Line:Neonatal mouse cardiomyocytes (NMCMs)Concentration:10, 33 and 100 μM Incubation Time:Half an hour before H/R injury Result:Inhibited disreoxygenation injury induced apoptosis.Western Blot Analysis Cell Line:Neonatal mouse cardiomyocytes (NMCMs ) Concentration:10, 33 and 100 μM Incubation Time:Half an hour before H/R injury Result:Significantly decreased the ratio of Bax/Bcl2 and cleaved-caspase 3 expression. Enhanced p-PI3K protein expression. cAMP levels were increased in the early stage and then gradually decreased.
  • In Vivo
    ——
  • Synonyms
    Phenylacetyl glycine | Phenaceturic acid
  • Pathway
    Others
  • Target
    Other Targets
  • Recptor
    Others
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    500-98-1
  • Formula Weight
    193.2
  • Molecular Formula
    C10H11NO3
  • Purity
    >98% (HPLC)
  • Solubility
    DMSO:196.7 mM
  • SMILES
    OC(=O)CNC(=O)Cc1ccccc1
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Kang SM et al. 1H nuclear magnetic resonance based metabolic urinary profiling of patients with ischemic heart failure. Clin Biochem. 2011 Mar;44(4):293-9.
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