(Thr4,Gly7)-Oxytocin
CAS No. 60786-59-6
(Thr4,Gly7)-Oxytocin( ——— )
Catalog No. M40317 CAS No. 60786-59-6
(Thr4,Gly7)-Oxytocin, an Oxytocin analogue, is a specific OT receptor agonist. (Thr4,Gly7)-Oxytocin also excites subicular neurons via activation of TRPV1 channels, and depression of K+ channels. .
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
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Biological Information
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Product Name(Thr4,Gly7)-Oxytocin
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NoteResearch use only, not for human use.
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Brief Description(Thr4,Gly7)-Oxytocin, an Oxytocin analogue, is a specific OT receptor agonist. (Thr4,Gly7)-Oxytocin also excites subicular neurons via activation of TRPV1 channels, and depression of K+ channels. .
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Description(Thr4,Gly7)-Oxytocin, an Oxytocin analogue, is a specific OT receptor agonist. (Thr4,Gly7)-Oxytocin also excites subicular neurons via activation of TRPV1 channels, and depression of K+ channels. .
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In Vitro———
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In VivoAnimal Model:Swiss Webster mice Dosage:1 μM Administration:Intratracheal administration for 24 h Result:Excited 34.3% of aPVT neurons, 57.6% of mPVT neurons, and 60.0% of pPVT neurons. Increased the firing rate of TGOT-responsive PVT neurons in all subregions.
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Synonyms———
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PathwayOthers
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TargetOther Targets
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RecptorOT receptors, K+ channels.
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Research Area———
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Indication———
Chemical Information
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CAS Number60786-59-6
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Formula Weight940.1
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Molecular FormulaC39H61N11O12S2
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Purity>98% (HPLC)
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SolubilityDMSO : ≥ 100 mg/mL (106.37 mM ) H2O : ≥ 50 mg/mL (53.19 mM)
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SMILES———
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Lily R Barrett, et al. Oxytocin activation of paraventricular thalamic neurons promotes feeding motivation to attenuate stress-induced hypophagia. Neuropsychopharmacology. 2021 Apr;46(5):1045-1056. ?
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