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(Thr4,Gly7)-Oxytocin

CAS No. 60786-59-6

(Thr4,Gly7)-Oxytocin( ——— )

Catalog No. M40317 CAS No. 60786-59-6

(Thr4,Gly7)-Oxytocin, an Oxytocin analogue, is a specific OT receptor agonist. (Thr4,Gly7)-Oxytocin also excites subicular neurons via activation of TRPV1 channels, and depression of K+ channels. .

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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Biological Information

  • Product Name
    (Thr4,Gly7)-Oxytocin
  • Note
    Research use only, not for human use.
  • Brief Description
    (Thr4,Gly7)-Oxytocin, an Oxytocin analogue, is a specific OT receptor agonist. (Thr4,Gly7)-Oxytocin also excites subicular neurons via activation of TRPV1 channels, and depression of K+ channels. .
  • Description
    (Thr4,Gly7)-Oxytocin, an Oxytocin analogue, is a specific OT receptor agonist. (Thr4,Gly7)-Oxytocin also excites subicular neurons via activation of TRPV1 channels, and depression of K+ channels. .
  • In Vitro
    ———
  • In Vivo
    Animal Model:Swiss Webster mice Dosage:1 μM Administration:Intratracheal administration for 24 h Result:Excited 34.3% of aPVT neurons, 57.6% of mPVT neurons, and 60.0% of pPVT neurons. Increased the firing rate of TGOT-responsive PVT neurons in all subregions.
  • Synonyms
    ———
  • Pathway
    Others
  • Target
    Other Targets
  • Recptor
    OT receptors, K+ channels.
  • Research Area
    ———
  • Indication
    ———

Chemical Information

  • CAS Number
    60786-59-6
  • Formula Weight
    940.1
  • Molecular Formula
    C39H61N11O12S2
  • Purity
    >98% (HPLC)
  • Solubility
    DMSO : ≥ 100 mg/mL (106.37 mM ) H2O : ≥ 50 mg/mL (53.19 mM)
  • SMILES
    ———
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Lily R Barrett, et al. Oxytocin activation of paraventricular thalamic neurons promotes feeding motivation to attenuate stress-induced hypophagia. Neuropsychopharmacology. 2021 Apr;46(5):1045-1056. ?
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