Desmopressin acetate
CAS No. 62288-83-9
Desmopressin acetate( DDAVP )
Catalog No. M19931 CAS No. 62288-83-9
Desmopressin is the synthetic analog of the antidiuretic hormone arginine vasopressin. Vasopressin Receptor The antidiuretic properties of desmopressin have led to its use in polyuric conditions including primary nocturnal enuresis nocturia and diabetes insipidus.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 2MG | 56 | Get Quote |
|
| 5MG | 88 | Get Quote |
|
| 10MG | 133 | Get Quote |
|
| 25MG | 227 | Get Quote |
|
| 50MG | 341 | Get Quote |
|
| 100MG | 510 | Get Quote |
|
| 200MG | Get Quote | Get Quote |
|
| 500MG | Get Quote | Get Quote |
|
| 1G | Get Quote | Get Quote |
|
Biological Information
-
Product NameDesmopressin acetate
-
NoteResearch use only, not for human use.
-
Brief DescriptionDesmopressin is the synthetic analog of the antidiuretic hormone arginine vasopressin. Vasopressin Receptor The antidiuretic properties of desmopressin have led to its use in polyuric conditions including primary nocturnal enuresis nocturia and diabetes insipidus.
-
DescriptionDesmopressin is the synthetic analog of the antidiuretic hormone arginine vasopressin. Vasopressin Receptor The antidiuretic properties of desmopressin have led to its use in polyuric conditions including primary nocturnal enuresis nocturia and diabetes insipidus. Desmopressin works by limiting the amount of water that is eliminated in the urine. Desmopressin binds to V2 receptors in renal collecting ducts increasing water reabsorption. It also stimulates the release of von Willebrand factor from endothelial cells by acting on the V2 receptor.
-
In Vitro——
-
In Vivo——
-
SynonymsDDAVP
-
PathwayGPCR/G Protein
-
TargetVasopressin Receptor
-
RecptorVasopressin receptor 1|vasopressin receptor 1a|Vasopressin receptor 2
-
Research AreaCancer
-
IndicationCancer metastases; Haemorrhage
Chemical Information
-
CAS Number62288-83-9
-
Formula Weight1129.26
-
Molecular FormulaC48H68N14O14S2
-
Purity>98% (HPLC)
-
SolubilityDMSO: 10 mM;Water: 50 mg/mL;Ethanol: Soluble
-
SMILESCC(O)=O.NC(=O)CC[C@@H]1NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](Cc2ccc(O)cc2)NC(=O)CCSSC[C@H](NC(=O)[C@H](CC(N)=O)NC1=O)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCCNC(N)=N)C(=O)NCC(N)=O
-
Chemical Name——
Shipping & Storage Information
-
Storage(-20℃)
-
ShippingWith Ice Pack
-
Stability≥ 2 years
Reference
1.Kaufmann JE et al. Desmopressin (DDAVP) induces NO production in human endothelial cells via V2 receptor- and cAMP-mediated signaling. J Thromb Haemost. 2003 Apr;1(4):821-8.
molnova catalog
related products
-
Balovaptan
Balovaptan is a highly potent and selective brain-penetrant vasopressin 1a (hV1a) receptor antagonist.
-
Tolvaptan
Tolvaptan (OPC-41061) is a highly potent selective, competitive vasopressin V2-receptor antagonist with Ki of 0.43 nM.
-
TASP0390325
TASP0390325 is an orally active and high affinity arginine pressin receptor 1B (V1B receptor) antagonist that shows antidepressant and anxiolytic activity in animal studies and blocks V1B receptors in the anterior pituitary gland in vivo.
Cart
sales@molnova.com