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tetrahydroxyl diphenylethylene-2-o-gluco
CAS No. 55327-45-2
tetrahydroxyl diphenylethylene-2-o-gluco( EH-201 )
Catalog No. M19812 CAS No. 55327-45-2
EH-201 is a low MW inducer of erythropoietin. EH-201 induces expression of erythropoietin PPAR-γ coactivator 1α (PGC-1α) and haemoglobin in astrocytes and PC12 neuronal-like cells. In vivo EH-201 treatment restores memory impairment as assessed by the passive avoidance test in SD Aβ and KA mouse models.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 1 mL x 10 mM in DMSO | 101 | In Stock |
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| 5MG | 112 | In Stock |
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| 10MG | 180 | In Stock |
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| 25MG | 303 | In Stock |
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| 50MG | 445 | In Stock |
|
| 100MG | 638 | In Stock |
|
| 200MG | 886 | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
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Product Nametetrahydroxyl diphenylethylene-2-o-gluco
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NoteResearch use only, not for human use.
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Brief DescriptionEH-201 is a low MW inducer of erythropoietin. EH-201 induces expression of erythropoietin PPAR-γ coactivator 1α (PGC-1α) and haemoglobin in astrocytes and PC12 neuronal-like cells. In vivo EH-201 treatment restores memory impairment as assessed by the passive avoidance test in SD Aβ and KA mouse models.
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DescriptionEH-201 is a low MW inducer of erythropoietin. EH-201 induces expression of erythropoietin PPAR-γ coactivator 1α (PGC-1α) and haemoglobin in astrocytes and PC12 neuronal-like cells. In vivo EH-201 treatment restores memory impairment as assessed by the passive avoidance test in SD Aβ and KA mouse models. In the hippocampus of mice given EH-201 in their diet levels of erythropoietin PGC-1α and haemoglobin were increased. Treatment with EH-201 might be a therapeutic strategy for memory impairment in neurodegenerative disease physiological ageing or traumatic brain injury.
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In Vitro——
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In Vivo——
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SynonymsEH-201
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PathwayOthers
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TargetOther Targets
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RecptorOthers
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Research Area——
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Indication——
Chemical Information
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CAS Number55327-45-2
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Formula Weight406.38
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Molecular FormulaC20H22O9
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Purity>98% (HPLC)
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SolubilityDMSO:10 mM
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SMILESOC[C@H]1O[C@@H](Oc2c(O)cc(O)cc2\C=C\c2ccc(O)cc2)[C@H](O)[C@@H](O)[C@@H]1O
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Chemical Name(2S3R4S5S6R)-2-(24-dihydroxy-6-((E)-4-hydroxystyryl)phenoxy)-6-(hydroxymethyl)tetrahydro-2H-pyran-345-triol
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1.Activating mitochondrial function and haemoglobin expression with EH‐201 an inducer of erythropoietin in neuronal cells reverses memory impairment[J]. British Journal of Pharmacology 2015 172(19):4741-4756.
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