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Xylazine
CAS No. 7361-61-7
Xylazine( BAY 1470 )
Catalog No. M19052 CAS No. 7361-61-7
Xylazine is α2-adrenergic receptor agonist.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 50MG | 34 | In Stock |
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| 100MG | 45 | In Stock |
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| 200MG | Get Quote | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
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Product NameXylazine
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NoteResearch use only, not for human use.
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Brief DescriptionXylazine is α2-adrenergic receptor agonist.
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DescriptionXylazine is α2-adrenergic receptor agonist.
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In Vitro——
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In VivoXylazine (5.2 mg/kg; intraperitoneal injection; for 10-60 minutes; male Sprague-Dawley rats) administration alters mRNA expression and protein phosphorylation levels of AMPK signaling molecules, suggesting that the LKB1-AMPK pathway plays a role in the sedative and tranquilizing effects in the CNS caused by Xylazine treatment. Animal Model:Male Sprague-Dawley rats (160-180 g)Dosage:5.2 mg/kg Administration:Intraperitoneal injection; for 10 minutes, 20 minutes, 40 minutesor 60 minutes Result:Increased in AMPK activity in the cerebral cortex, hippocampus, thalamus and cerebellum. Phosphorylated LKB1 and AMPKα protein levels were decreased.
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SynonymsBAY 1470
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PathwayMetabolic Enzyme/Protease
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TargetP450
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Recptorα2-adrenergic receptor
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Research AreaNeurological Disease
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Indication——
Chemical Information
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CAS Number7361-61-7
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Formula Weight220.33
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Molecular FormulaC12H16N2S
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Purity>98% (HPLC)
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Solubility——
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SMILESCc1cccc(C)c1NC1=NCCCS1
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
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CYP1B1-IN-4
CYP1B1-IN-4, a 2,4-diarylthiazole compound, exhibits selective inhibition of CYP1B1 (IC50=0.2 nM), demonstrating minimal cytotoxicity and high stability in human and rat liver microsomes .
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Rhodionin
Rhodionin and rhodionin can inhibit cytochrome P450 2D6 non-competitively with high specificity which could have implications for interactions with co-administered drugs; they can significantly suppress the elevation of the postprandial blood triglyceride level suggests that they may be to the treatment of lifestyle-related diseases such as hyperlipidemia and exogeneous obesity and to health foods.
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Isoasatone A
Isoasatone A acts against S. litura by acting on cytochrome P450 monooxygenase and glutathione transferase. Isoasatone A is a natural product isolated from Heterotropa takaoi M..
