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CYP1B1-IN-4
CAS No. 2685779-55-7
CYP1B1-IN-4( —— )
Catalog No. M36490 CAS No. 2685779-55-7
CYP1B1-IN-4, a 2,4-diarylthiazole compound, exhibits selective inhibition of CYP1B1 (IC50=0.2 nM), demonstrating minimal cytotoxicity and high stability in human and rat liver microsomes .
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 1 mL x 10 mM in DMSO | 43 | In Stock |
|
| 5MG | 31 | In Stock |
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| 10MG | 50 | In Stock |
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| 25MG | 102 | In Stock |
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| 50MG | 161 | In Stock |
|
| 100MG | 239 | In Stock |
|
| 200MG | 352 | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
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Product NameCYP1B1-IN-4
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NoteResearch use only, not for human use.
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Brief DescriptionCYP1B1-IN-4, a 2,4-diarylthiazole compound, exhibits selective inhibition of CYP1B1 (IC50=0.2 nM), demonstrating minimal cytotoxicity and high stability in human and rat liver microsomes .
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DescriptionCYP1B1-IN-4 is a 2,4-diarylthiazole compound with selectively CYP1B1 inhibition (IC50=0.2 nM). CYP1B1-IN-4 has little cytotoxicity and high stability in both human and rat liver microsomes.
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In Vitro——
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In Vivo——
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Synonyms——
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PathwayMetabolic Enzyme/Protease
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TargetP450
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RecptorP450
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Research Area——
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Indication——
Chemical Information
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CAS Number2685779-55-7
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Formula Weight322.38
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Molecular FormulaC18H14N2O2S
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Purity>98% (HPLC)
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SolubilityIn Vitro:?DMSO : 62.5 mg/mL (193.87 mM; Ultrasonic )
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SMILESO(C)C1=C(C2=NC(=CS2)C3=CC=C(C#N)C=C3)C=CC(OC)=C1
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Hachey AC, et al. Design of Cytochrome P450 1B1 Inhibitors via a Scaffold-Hopping Approach. J Med Chem. 2022 Dec 15. ?
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