Isoasatone A
CAS No. 67451-73-4
Isoasatone A( —— )
Catalog No. M26260 CAS No. 67451-73-4
Isoasatone A acts against S. litura by acting on cytochrome P450 monooxygenase and glutathione transferase. Isoasatone A is a natural product isolated from Heterotropa takaoi M..
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 5MG | 252 | Get Quote |
|
| 10MG | 374 | Get Quote |
|
| 25MG | 620 | Get Quote |
|
| 50MG | 885 | Get Quote |
|
| 100MG | 1197 | Get Quote |
|
| 200MG | Get Quote | Get Quote |
|
| 500MG | Get Quote | Get Quote |
|
| 1G | Get Quote | Get Quote |
|
Biological Information
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Product NameIsoasatone A
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NoteResearch use only, not for human use.
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Brief DescriptionIsoasatone A acts against S. litura by acting on cytochrome P450 monooxygenase and glutathione transferase. Isoasatone A is a natural product isolated from Heterotropa takaoi M..
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DescriptionIsoasatone A acts against S. litura by acting on cytochrome P450 monooxygenase and glutathione transferase. Isoasatone A is a natural product isolated from Heterotropa takaoi M.
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In Vitro——
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In Vivo——
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Synonyms——
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PathwayMetabolic Enzyme/Protease
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TargetP450
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RecptorGlyT1
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Research Area——
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Indication——
Chemical Information
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CAS Number67451-73-4
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Formula Weight448.512
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Molecular FormulaC24H32O8
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Purity>98% (HPLC)
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Solubility——
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SMILES[H][C@]12C(\C=C\C)=C[C@](OC)(C(=O)C1(OC)OC)C1(CC=C)C=C(OC)C(=O)C(OC)(OC)[C@@]21[H]
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
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PF-4981517
PF-4981517 (CYP3cide) is a efficient, specific and time-dependent inhibitor of cytochrome P4503A4 (CYP3A4). The IC 50 values for CYP3A activity are 0.03 μM,17 μM, and 71 μM for CYP3A4, CYP3A5, and CYP3A7, respectively.
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N-Nornuciferine hydr...
N-Nornuciferine is an aporphine alkaloid in lotus leaf, significantly inhibits CYP2D6 (IC50: 3.76 μM, Ki: 2.34 μM).N-Nornuciferine strongly inhibits CYP2D6 activity but shows weak or no inhibition of the other four P450 isoenzymes (CYP2C19, CYP3A4, CYP2E1, CYP2C9). N-Nornuciferine competitively inhibits the CYP2D6-catalyzed dextromethorphan O-demethylation (Ki: 2.34 μM).
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7-Ethoxyresorufin
7-Ethoxyresorufin (7-ER) is a fluorometric substrate for and competitive inhibitor of cytochrome P450, especially CYP1A1.
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