Isosorbide

Research use only, not for human use.

Isosorbide is a heterocyclic compound that is derived from glucose, used as a diuretic.

Isosorbide is a precursor of Isosorbide mononitrate or dinitrate, which relax vascular smooth muscle by formation of the free radical nitric oxide (NO).

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Isosorbide (5 mg/kg; a single p.o.) significantly increases the urine volume of rats within 2 hours which lasts through the 8 hour experimental period.Isosorbide (5 mg/kg; a single p.o. 30 min prior to gallium injection) significantly reduces the urinary concentrations of both gallium and calcium in rats.Isosorbide (5 mg/kg; p.o. 30 min prior to gallium injection for 6 d) results in the formation of fewer renal precipitates and histopathologic changes than in the nondiuresed animals.

Isosorbide | Devicoran | Hydronol

Others

Other Targets

Others

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652-67-5

146.14

C6H10O4

>98% (HPLC)

H2O : ≥ 42 mg/mL; 287.40 mM

[H][C@]12OC[C@@H](O)[C@@]1([H])OC[C@@H]2O

(3S,3aR,6R,6aR)-2,3,3a,5,6,6a-Hexahydrofuro[3,2-b]furan-3,6-diol

(-20℃)

With Ice Pack

≥ 2 years