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EAAT2 activator 1

CAS No. 892415-28-0

EAAT2 activator 1( F2005-0304 | 3-[(2-Chloro-6-fluorobenzyl)thio]-6-pyridin-2-ylpyridazine )

Catalog No. M28620 CAS No. 892415-28-0

F2005-0304 is a thiopyridazine derivative that has been found to increase EAAT2 protein levels in astrocytes.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
1 mL x 10 mM in DMSO 35 In Stock
5MG 31 In Stock
10MG 55 In Stock
25MG 113 In Stock
50MG 205 In Stock
100MG 305 In Stock
200MG 434 In Stock
500MG Get Quote In Stock
1G Get Quote In Stock
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Biological Information

  • Product Name
    EAAT2 activator 1
  • Note
    Research use only, not for human use.
  • Brief Description
    F2005-0304 is a thiopyridazine derivative that has been found to increase EAAT2 protein levels in astrocytes.
  • Description
    F2005-0304 is a thiopyridazine derivative that has been found to increase EAAT2 protein levels in astrocytes.
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    F2005-0304 | 3-[(2-Chloro-6-fluorobenzyl)thio]-6-pyridin-2-ylpyridazine
  • Pathway
    Others
  • Target
    Other Targets
  • Recptor
    BD1-BRD4|BRD4-BD2
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    892415-28-0
  • Formula Weight
    331.8
  • Molecular Formula
    C16H11ClFN3S
  • Purity
    >98% (HPLC)
  • Solubility
    In Vitro:?DMSO : 25 mg/mL (75.35 mM)
  • SMILES
    Fc1cccc(Cl)c1CSc(cc1)nnc1-c1ncccc1
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Kharenko OA, et al. Design and Characterization of Novel Covalent Bromodomain and Extra-Terminal Domain (BET) Inhibitors Targeting a Methionine. J Med Chem. 2018 Sep 27;61(18):8202-8211.
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