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CLOZAPINE N-OXIDE
CAS No. 34233-69-7
CLOZAPINE N-OXIDE( Clozapine N-oxide )
Catalog No. M18447 CAS No. 34233-69-7
Clozapine N-oxide is a major metabolite of clozapine that can be detected in the earliest excretion time interval after clozapine administration.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 2MG | 29 | In Stock |
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| 5MG | 43 | In Stock |
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| 10MG | 72 | In Stock |
|
| 25MG | 120 | In Stock |
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| 50MG | 174 | In Stock |
|
| 100MG | 259 | In Stock |
|
| 200MG | Get Quote | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
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Product NameCLOZAPINE N-OXIDE
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NoteResearch use only, not for human use.
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Brief DescriptionClozapine N-oxide is a major metabolite of clozapine that can be detected in the earliest excretion time interval after clozapine administration.
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DescriptionClozapine N-oxide is a major metabolite of clozapine that can be detected in the earliest excretion time interval after clozapine administration. It is produced by the action of cytochrome P450 (CYP) isoforms CYP1A2 and CYP3A4, whose activities, in turn, can be affected by drugs and disease. Clozapine N-oxide is normally biologically inactive. However, it can be used in designer receptor exclusively activated by designer drugs, also known as DREADDs, technology to modulate synthetic receptors in vivo.
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In Vitro——
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In Vivo——
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SynonymsClozapine N-oxide
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PathwayOthers
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TargetOther Targets
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RecptorOthers
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Research AreaNeurological Disease
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Indication——
Chemical Information
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CAS Number34233-69-7
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Formula Weight342.82
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Molecular FormulaC18H19ClN4O
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Purity>98% (HPLC)
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SolubilityDMSO : ≥ 100 mg/mL 291.70 mM; Methanol : ≥ 28.6 mg/mL 83.43 mM H2O : 1 mg/mL 2.92 mM
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SMILESClc1ccc2Nc4ccccc4C(=Nc2c1)N3CC[N+]([O-])(C)CC3
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Chemical Name3-Chloro-6-(4-methyl-4-oxidopiperazin-4-ium-1-yl)-5H-benzo[b][1,4]benzodiazepine
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Dain, J.G., et al. Biotransformation of clozapine in humans. Drug Metabolism and Disposition 25(5), 603-609 (1997).
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