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Fargesin
CAS No. 31008-19-2
Fargesin( Fargesin )
Catalog No. M18407 CAS No. 31008-19-2
Fargesin as a potential β1AR antagonist through cAMP/PKA pathway could protect against myocardial ischemia/reperfusion injury in rats.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 1 mL x 10 mM in DMSO | 67 | In Stock |
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| 5MG | 61 | In Stock |
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| 10MG | 107 | In Stock |
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| 25MG | 185 | In Stock |
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| 50MG | 297 | In Stock |
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| 100MG | 442 | In Stock |
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| 200MG | Get Quote | In Stock |
|
| 500MG | Get Quote | In Stock |
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| 1G | Get Quote | In Stock |
|
Biological Information
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Product NameFargesin
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NoteResearch use only, not for human use.
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Brief DescriptionFargesin as a potential β1AR antagonist through cAMP/PKA pathway could protect against myocardial ischemia/reperfusion injury in rats.
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DescriptionFargesin is a lignan from Magnolia fargesii, an oriental medicine used in the treatment of nasal congestion and sinusitis. Fargesin exhibits anti-inflammation effects on THP-1 cells via suppression of PKC pathway including downstream JNK, nuclear factors AP-1 and NF- B. Fargesin as a potential β adrenergic receptor antagonist protects the hearts against ischemia/reperfusion injury in rats via attenuating oxidative stress and apoptosis.(In Vitro):Fargesin exhibits anti-inflammation effects on THP-1 cells via suppression of PKC pathway including downstream JNK, nuclear factors AP-1 and NF- B.Fargesin as a potential β adrenergic receptor antagonist protects the hearts against ischemia/reperfusion injury in rats via attenuating oxidative stress and apoptosis.(In Vivo):Fargesin has antihypertensive effect in 2K1C hypertensive rats via inhibiting oxidative stress and promoting NO release.
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In VitroFargesin exhibits anti-inflammation effects on THP-1 cells via suppression of PKC pathway including downstream JNK, nuclear factors AP-1 and NF-?B. Fargesin as a potential β? adrenergic receptor antagonist protects the hearts against ischemia/reperfusion injury in rats via attenuating oxidative stress and apoptosis.
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In VivoFargesin has antihypertensive effect in 2K1C hypertensive rats via inhibiting oxidative stress and promoting NO release.
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SynonymsFargesin
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PathwayAngiogenesis
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TargetVEGFR
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Recptorβ1-adrenergic receptor
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Research Area——
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Indication——
Chemical Information
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CAS Number31008-19-2
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Formula Weight370.4
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Molecular FormulaC21H22O6
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Purity>98% (HPLC)
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SolubilityIn Vitro:?DMSO : 125 mg/mL (337.47 mM)
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SMILESCOC1=C(C=C(C=C1)C2C3COC(C3CO2)C4=CC5=C(C=C4)OCO5)OC
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Chemical Name1H,3H-Furo(3,4-C)furan, 1alpha-(3,4-dimethoxyphenyl)-3abeta,4,6,6abeta-tetrahydro-4beta-((3,4-methylenedioxy)phenyl)-
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
molnova catalog
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