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Senegenin
CAS No. 2469-34-3
Senegenin( —— )
Catalog No. M18304 CAS No. 2469-34-3
Senegenin is a natural product from Polygala tenuifolia used in Chinese medicine with antioxidative and anti-inflammatory activity.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 1 mL x 10 mM in DMSO | 57 | In Stock |
|
| 2MG | 29 | In Stock |
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| 5MG | 46 | In Stock |
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| 10MG | 67 | In Stock |
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| 25MG | 107 | In Stock |
|
| 50MG | 152 | In Stock |
|
| 100MG | 222 | In Stock |
|
| 200MG | 328 | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
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Product NameSenegenin
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NoteResearch use only, not for human use.
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Brief DescriptionSenegenin is a natural product from Polygala tenuifolia used in Chinese medicine with antioxidative and anti-inflammatory activity.
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DescriptionSenegenin is a natural product from Polygala tenuifolia used in Chinese medicine with antioxidative and anti-inflammatory activity.
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In Vitro——
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In VivoTenuigenin (2, 4, 8 mg/kg) significantly attenuates S.aureus-induced lung histopathological changes. Tenuigenin also inhibits lung wet/dry (W/D) ratio, and inflammatory cytokines TNF-α and IL-1β production in Male BALB/c mice.
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Synonyms——
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PathwayMAPK/ERK Signaling
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Targetp38 MAPK
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RecptorCaspase-3
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Research Area——
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Indication——
Chemical Information
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CAS Number2469-34-3
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Formula Weight537.1
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Molecular FormulaC30H45ClO6
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Purity>98% (HPLC)
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SolubilityIn Vitro:?DMSO : 100 mg/mL (186.17 mM)
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SMILESC1[C@@H]([C@@H]([C@]([C@@H]2CC[C@]3(C4=C([C@H]5[C@@](CC4)(CCC(C5)(C)C)C(=O)O)[C@H](C[C@@H]3[C@@]12C)CCl)C)(C(=O)O)C)O)O
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1.Li X, Zhao Y, Liu P,et al.Senegenin Inhibits Hypoxia/Reoxygenation-Induced Neuronal Apoptosis by Upregulating RhoGDIα.Mol Neurobiol. 2015 Dec;52(3):1561-71.
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