Senegenin

CAS No. 2469-34-3

Senegenin( —— )

Catalog No. M18304 CAS No. 2469-34-3

Senegenin is a natural product from Polygala tenuifolia used in Chinese medicine with antioxidative and anti-inflammatory activity.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
1 mL x 10 mM in DMSO 57 In Stock
2MG 29 In Stock
5MG 46 In Stock
10MG 67 In Stock
25MG 107 In Stock
50MG 152 In Stock
100MG 222 In Stock
200MG 328 In Stock
500MG Get Quote In Stock
1G Get Quote In Stock

Biological Information

  • Product Name
    Senegenin
  • Note
    Research use only, not for human use.
  • Brief Description
    Senegenin is a natural product from Polygala tenuifolia used in Chinese medicine with antioxidative and anti-inflammatory activity.
  • Description
    Senegenin is a natural product from Polygala tenuifolia used in Chinese medicine with antioxidative and anti-inflammatory activity.
  • In Vitro
    ——
  • In Vivo
    Tenuigenin (2, 4, 8 mg/kg) significantly attenuates S.aureus-induced lung histopathological changes. Tenuigenin also inhibits lung wet/dry (W/D) ratio, and inflammatory cytokines TNF-α and IL-1β production in Male BALB/c mice.
  • Synonyms
    ——
  • Pathway
    MAPK/ERK Signaling
  • Target
    p38 MAPK
  • Recptor
    Caspase-3
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    2469-34-3
  • Formula Weight
    537.1
  • Molecular Formula
    C30H45ClO6
  • Purity
    >98% (HPLC)
  • Solubility
    In Vitro:?DMSO : 100 mg/mL (186.17 mM)
  • SMILES
    C1[C@@H]([C@@H]([C@]([C@@H]2CC[C@]3(C4=C([C@H]5[C@@](CC4)(CCC(C5)(C)C)C(=O)O)[C@H](C[C@@H]3[C@@]12C)CCl)C)(C(=O)O)C)O)O
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Li X, Zhao Y, Liu P,et al.Senegenin Inhibits Hypoxia/Reoxygenation-Induced Neuronal Apoptosis by Upregulating RhoGDIα.Mol Neurobiol. 2015 Dec;52(3):1561-71.
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