Cart
sales@molnova.com
SKLB-163
CAS No. 1255099-06-9
SKLB-163( SKLB 163 | SKLB163 )
Catalog No. M27829 CAS No. 1255099-06-9
SKLB-163 acts by downregulating RhoGDI, activating JNK-1 signaling pathway and caspase-3, and reducing phosphorylated Akt and p44/42 MAPK.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 1 mL x 10 mM in DMSO | 354 | In Stock |
|
| 5MG | 319 | In Stock |
|
| 10MG | 472 | In Stock |
|
| 25MG | 753 | In Stock |
|
| 50MG | 1051 | In Stock |
|
| 100MG | 1414 | In Stock |
|
| 200MG | Get Quote | In Stock |
|
| 500MG | 2762 | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
-
Product NameSKLB-163
-
NoteResearch use only, not for human use.
-
Brief DescriptionSKLB-163 acts by downregulating RhoGDI, activating JNK-1 signaling pathway and caspase-3, and reducing phosphorylated Akt and p44/42 MAPK.
-
DescriptionSKLB-163 acts by downregulating RhoGDI, activating JNK-1 signaling pathway and caspase-3, and reducing phosphorylated Akt and p44/42 MAPK.
-
In Vitro——
-
In Vivo——
-
SynonymsSKLB 163 | SKLB163
-
PathwayMAPK/ERK Signaling
-
Targetp38 MAPK
-
RecptorGABAA
-
Research Area——
-
Indication——
Chemical Information
-
CAS Number1255099-06-9
-
Formula Weight405.92
-
Molecular FormulaC18H16ClN3O2S2
-
Purity>98% (HPLC)
-
Solubility——
-
SMILESClCC(=O)Nc1ccc2nc(SCC(=O)NCc3ccccc3)sc2c1
-
Chemical Name——
Shipping & Storage Information
-
Storage(-20℃)
-
ShippingWith Ice Pack
-
Stability≥ 2 years
Reference
1.Divya K Nair, et al. Synthesis of imidazopyridines from the Morita-Baylis-Hillman acetates of nitroalkenes and convenient access to Alpidem and Zolpidem. Org Lett. 2012 Sep 7;14(17):4580-3.
molnova catalog
related products
-
MK2-IN-3
MK2-IN-3 is a potent, cell-permeable inhibitor of mitogen-activated protein kinase-activated protein kinase 2 (MAPKAP-K2 or MK-2) and can be used for the treatment of rheumatoid arthritis
-
JNJ-49095397
JNJ-49095397 (RV-568) is a specific narrow-spectrum kinase inhibitor that inhibits a selected set of kinases involved in COPD inflammation with IC50 of 5, 40 and 52 nM for p38α, p38γ and HCK, respectively.
-
MW181 hydrochloride
MW181 (MW01-10-181SRM) is an isoform-selective, brain-permeable, and orally bioavailable small molecule inhibitor of p38α MAPK with Ki of 184 nM.
