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BMY 7378 dihydrochloride
CAS No. 21102-95-4
BMY 7378 dihydrochloride( —— )
Catalog No. M18235 CAS No. 21102-95-4
BMY-7378, α1D-adrenergic receptor antagonist, is a weak partial agonist/antagonist of 5-HT1A receptor.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 10MG | 45 | In Stock |
|
| 25MG | 73 | In Stock |
|
| 50MG | 93 | In Stock |
|
| 200MG | 332 | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
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Product NameBMY 7378 dihydrochloride
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NoteResearch use only, not for human use.
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Brief DescriptionBMY-7378, α1D-adrenergic receptor antagonist, is a weak partial agonist/antagonist of 5-HT1A receptor.
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DescriptionBMY-7378, α1D-adrenergic receptor antagonist, is a weak partial agonist/antagonist of 5-HT1A receptor.
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In VitroBMY 7378 is selective for the alpha 1D-adrenoceptor subtype (pKi: hamster alpha 1b-adrenoceptor 6.2, human alpha 1b-adrenoceptor 7.2; bovine alpha 1c-adrenoceptor 6.1, human alpha 1c-adrenoceptor 6.6; rat alpha 1d-adrenoceptor 8.2, human alpha 1d-adrenoceptor 9.4) and has high affinity (pA2, 8.9) for rat aorta alpha 1-adrenoceptor.
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In Vivo——
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Synonyms——
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PathwayOthers
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TargetAntioxidant
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Recptor5-HT1A| 5-HT1C| α1D-adrenoceptor| α2C-adrenoceptor| D2
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Research AreaNeurological Disease
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Indication——
Chemical Information
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CAS Number21102-95-4
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Formula Weight458.42
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Molecular FormulaC22H33Cl2N3O3
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Purity>98% (HPLC)
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Solubility——
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SMILESCl.COc1ccccc1N1CCN(CCN2C(=O)CC3(CCCC3)CC2=O)CC1.Cl
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Cleary L, et al. Auton Autacoid Pharmacol. 2005 Oct;25(4):135-41.
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