Home - Products - GPCR/G Protein - GHSR - TAPI-1

TAPI-1

CAS No. 171235-71-5

TAPI-1( TAPI-1 | TNF-alpha Protease Inhibitor-1 )

Catalog No. M18119 CAS No. 171235-71-5

TAPI-1, an ADAM17/TACE inhibitor, inhibits shedding of cytokine receptors.

Purity : >98% (HPLC)

COA

Datasheet

HNMR

HPLC

MSDS

Handing Instructions

Size	Price / USD	Stock	Quantity
25MG	1476	In Stock
50MG	2232	In Stock
100MG	Get Quote	In Stock
200MG	Get Quote	In Stock
500MG	Get Quote	In Stock
1G	Get Quote	In Stock

Get Quotation Bulk Inquiry Add to Cart

Biological Information

Product Name

TAPI-1
Note

Research use only, not for human use.
Brief Description

TAPI-1, an ADAM17/TACE inhibitor, inhibits shedding of cytokine receptors.
Description

TAPI-1 is and inhibitor of TACE. It inhibits the cleavage of TNF-a, TNFRI (p60), and TNFRII (p80).
In Vitro

——
In Vivo

——
Synonyms

TAPI-1 | TNF-alpha Protease Inhibitor-1
Pathway

GPCR/G Protein
Target

GHSR
Recptor

ADAM17/TACE
Research Area

Cancer
Indication

——

Chemical Information

CAS Number

171235-71-5
Formula Weight

499.6
Molecular Formula

C26H37N5O5
Purity

>98% (HPLC)
Solubility

——
SMILES

CC(C)CC(CC(=O)NO)C(=O)N[C@@H](Cc1cc2ccccc2cc1)C(=O)N[C@@H](C)C(=O)NCCN
Chemical Name

N-[(2S)-1-[[(2S)-1-(2-Aminoethylamino)-1-oxopropan-2-yl]amino]-3-naphthalen-2-yl-1-oxopropan-2-yl]-N'-hydroxy-2-(2-methylpropyl)butanediamide

Shipping & Storage Information

Storage

(-20℃)
Shipping

With Ice Pack
Stability

≥ 2 years

Reference

1. Müllberg J, et al. J Immunol. 1995, 155(11), 5198-5205.

Calculator

Molecular Weight Calculator

Dilution Calculator

Molarity Calculator

molnova catalog

related products

Relamorelin

Relamorelin(BIM28131, RM131) is a selective and potent ghrelin/growth hormone secretagogue receptor (GHSR) agonist with high affinity for GHS-1a receptor (Ki value is 0.42 ± 0.063 nM).
Livoletide

A first-in-class analogue of unacylated ghrelin, and unacylated ghrelin receptor agonist.
K-(D-1-Nal)-FwLL-NH2

High affinity and potent ghrelin receptor inverse agonist (Ki values are 4.9 and 31 nM in COS7 and HEK293T cells, respectively). Blocks ghrelin receptor-mediated Gq- and G13-dependent signaling pathways.

Sign In Join Free