Cart
sales@molnova.com
Home - Products - Others - Other Targets - Dolasetron

Dolasetron

CAS No. 115956-12-2

Dolasetron( HSDB 7565 | HSDB7565 | Dolasetron | Dolasetronum )

Catalog No. M17847 CAS No. 115956-12-2

Dolasetron(MDL-73147) is a serotonin 5-HT3 receptor antagonist used to treat nausea and vomiting following chemotherapy.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
1 mL x 10 mM in DMSO 42 In Stock
5MG 38 In Stock
10MG 57 In Stock
25MG 117 In Stock
50MG 184 In Stock
100MG 276 In Stock
200MG Get Quote In Stock
500MG 682 In Stock
1G Get Quote In Stock
Get Quotation Bulk Inquiry Add to Cart

Biological Information

  • Product Name
    Dolasetron
  • Note
    Research use only, not for human use.
  • Brief Description
    Dolasetron(MDL-73147) is a serotonin 5-HT3 receptor antagonist used to treat nausea and vomiting following chemotherapy.
  • Description
    Dolasetron is a serotonin 5-HT3 receptor antagonist used to treat nausea and vomiting following chemotherapy. Its main effect is to reduce the activity of the vagus nerve, which is a nerve that activates the vomiting center in the medulla oblongata. It does not have much antiemetic effect when symptoms are due to motion sickness. This drug does not have any effect on dopamine receptors or muscarinic receptors.
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    HSDB 7565 | HSDB7565 | Dolasetron | Dolasetronum
  • Pathway
    Others
  • Target
    Other Targets
  • Recptor
    5-HT3
  • Research Area
    Others-Field
  • Indication
    ——

Chemical Information

  • CAS Number
    115956-12-2
  • Formula Weight
    324.38
  • Molecular Formula
    C19H20N2O3
  • Purity
    >98% (HPLC)
  • Solubility
    DMSO : ≥ 300 mg/mL; 924.87 mM
  • SMILES
    [H][C@]12C[C@@H](C[C@@H]3C[C@H](C1)C(=O)CN23)OC(=O)c1c[nH]c2ccccc12
  • Chemical Name
    (6R)-3-oxooctahydro-1H-2,6-methanoquinolizin-8-yl 1H-indole-3-carboxylate

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Faria C,etal.Outcomes Associated with 5-HT3-RA Therapy Selection in Patients with Chemotherapy-Induced Nausea and Vomiting: A Retrospective Claims Analysis.Am Health Drug Benefits. 2014 Jan;7(1):50-8.
Calculator

Molecular Weight Calculator

Dilution Calculator

Molarity Calculator

molnova catalog
related products

  • 8,8-Bibaicalein

    8,8''-Bibaicalein is a natural product from Scutellaria baicalensis.

  • Vestitol

    Vestitol is a phytoalexin with insect feeding-deterrent activity, it has antioxidant, anti-inflammatory and antimicrobial activities, it can inhibit neutrophil migration at a dose of 10 mg/kg, and shows MICs ranging from 25-50 to 50-100 ug/mL and MBCs ranging from 25-50 to 50-100 ug/mL.

  • Artemisinin

    Artemisinin is a drug used to treat multi-drug resistant strains of falciparum malaria (as well as increasingly vivax malaria).

Sign In Join Free