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WR-99210

CAS No. 30711-93-4

WR-99210( 6,6-Dimethyl-1-[3-(2,4,5-trichlorophenoxy)propoxy]-1,6-dihydro-1,3,5-triazine-2,4-diamine | WR99210 hydrochloride(47326-86-3 free base) )

Catalog No. M24237 CAS No. 30711-93-4

WR-99210 is a potent inhibitor of Plasmodium falciparum dihydrofolate reductase (pfDHFR), which is a major malarial drug target.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
1 mL x 10 mM in DMSO 160 In Stock
5MG 135 In Stock
10MG 211 In Stock
25MG 356 In Stock
50MG 513 In Stock
100MG 732 In Stock
200MG 986 In Stock
500MG Get Quote In Stock
1G Get Quote In Stock
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Biological Information

  • Product Name
    WR-99210
  • Note
    Research use only, not for human use.
  • Brief Description
    WR-99210 is a potent inhibitor of Plasmodium falciparum dihydrofolate reductase (pfDHFR), which is a major malarial drug target.
  • Description
    WR-99210 is a potent inhibitor of Plasmodium falciparum dihydrofolate reductase (pfDHFR), which is a major malarial drug target. It has subnanomolar potency for the wild type, double mutant and quadruple mutant dihydrofolate reductases.
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    6,6-Dimethyl-1-[3-(2,4,5-trichlorophenoxy)propoxy]-1,6-dihydro-1,3,5-triazine-2,4-diamine | WR99210 hydrochloride(47326-86-3 free base)
  • Pathway
    Others
  • Target
    Other Targets
  • Recptor
    pfDHFR
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    30711-93-4
  • Formula Weight
    431.14
  • Molecular Formula
    C14H19Cl4N5O2
  • Purity
    >98% (HPLC)
  • Solubility
    ——
  • SMILES
    NC1=NC(N)=NC(C)(C)N1OCCCOC2=CC(Cl)=C(Cl)C=C2Cl.[H]Cl
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Canfield C J , Milhous W K , Ager A L , et al. PS-15: a potent, orally active antimalarial from a new class of folic acid antagonists.[J]. American Journal of Tropical Medicine & Hygiene, 1993, 49(1):121.
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