WR-99210
CAS No. 30711-93-4
WR-99210( 6,6-Dimethyl-1-[3-(2,4,5-trichlorophenoxy)propoxy]-1,6-dihydro-1,3,5-triazine-2,4-diamine | WR99210 hydrochloride(47326-86-3 free base) )
Catalog No. M24237 CAS No. 30711-93-4
WR-99210 is a potent inhibitor of Plasmodium falciparum dihydrofolate reductase (pfDHFR), which is a major malarial drug target.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 1 mL x 10 mM in DMSO | 160 | In Stock |
|
| 5MG | 135 | In Stock |
|
| 10MG | 211 | In Stock |
|
| 25MG | 356 | In Stock |
|
| 50MG | 513 | In Stock |
|
| 100MG | 732 | In Stock |
|
| 200MG | 986 | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
-
Product NameWR-99210
-
NoteResearch use only, not for human use.
-
Brief DescriptionWR-99210 is a potent inhibitor of Plasmodium falciparum dihydrofolate reductase (pfDHFR), which is a major malarial drug target.
-
DescriptionWR-99210 is a potent inhibitor of Plasmodium falciparum dihydrofolate reductase (pfDHFR), which is a major malarial drug target. It has subnanomolar potency for the wild type, double mutant and quadruple mutant dihydrofolate reductases.
-
In Vitro——
-
In Vivo——
-
Synonyms6,6-Dimethyl-1-[3-(2,4,5-trichlorophenoxy)propoxy]-1,6-dihydro-1,3,5-triazine-2,4-diamine | WR99210 hydrochloride(47326-86-3 free base)
-
PathwayOthers
-
TargetOther Targets
-
RecptorpfDHFR
-
Research Area——
-
Indication——
Chemical Information
-
CAS Number30711-93-4
-
Formula Weight431.14
-
Molecular FormulaC14H19Cl4N5O2
-
Purity>98% (HPLC)
-
Solubility——
-
SMILESNC1=NC(N)=NC(C)(C)N1OCCCOC2=CC(Cl)=C(Cl)C=C2Cl.[H]Cl
-
Chemical Name——
Shipping & Storage Information
-
Storage(-20℃)
-
ShippingWith Ice Pack
-
Stability≥ 2 years
Reference
1.Canfield C J , Milhous W K , Ager A L , et al. PS-15: a potent, orally active antimalarial from a new class of folic acid antagonists.[J]. American Journal of Tropical Medicine & Hygiene, 1993, 49(1):121.
molnova catalog
related products
-
Acetyllycoposerramin...
Acetyllycoposerramine M is a lycopodine-type alkaloid, which can be isolated from Lycopodium japonicum. But Acetyllycoposerramine M has no inhibitory effect on acetylcholinesterase.
-
Octyl-beta-D-glucopy...
Octyl-beta-D-glucopyranoside (11β-HSD1-IN-11) is a non-ionic detergent, it can be widely used in the research of biotechnical, biochemical applications, solubilization and crystallization of membrane proteins.
-
Pyruvic acid
Pyruvic acid is an intermediate compound in the metabolism of carbohydrates proteins and fats. In thiamine deficiency its oxidation is retarded and it accumulates in the tissues especially in nervous structures.
Cart
sales@molnova.com