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PEAQX
CAS No. 459836-30-7
PEAQX( NVP-AAM077 | NVP-AAM 077 | NVP-AAM-077 )
Catalog No. M17513 CAS No. 459836-30-7
PEAQX(NVP-AAM 077) is an effective and orally available NMDA antagonist. It can inhibit human NMDA receptors for 1A/2A(IC50: 270 nM), rather than 1A/2B(29, 600 nM).
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 2MG | 58 | In Stock |
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| 5MG | 105 | In Stock |
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| 10MG | 190 | In Stock |
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| 25MG | 342 | In Stock |
|
| 50MG | 532 | In Stock |
|
| 100MG | 759 | In Stock |
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| 200MG | Get Quote | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
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Product NamePEAQX
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NoteResearch use only, not for human use.
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Brief DescriptionPEAQX(NVP-AAM 077) is an effective and orally available NMDA antagonist. It can inhibit human NMDA receptors for 1A/2A(IC50: 270 nM), rather than 1A/2B(29, 600 nM).
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DescriptionPEAQX, also known as NVP-AAM077; is a competitive antagonist at the NMDA receptor. Although originally described as 100-fold selective for GluN1/GluN2A receptors vs. GluN1/GluN2B receptors, more detailed studies of the Ki of PEAQX revealed it only shows a 5 fold difference in affinity for GluN1/GluN2A vs. GluN1/GluN2B receptors. It is also a potent anticonvulsant in animal tests.
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In Vitro——
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In Vivo——
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SynonymsNVP-AAM077 | NVP-AAM 077 | NVP-AAM-077
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PathwayNeuroscience
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TargetGamma-secretase
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RecptorhNMDA 1A/2A receptors
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Research AreaNeurological Disease
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Indication——
Chemical Information
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CAS Number459836-30-7
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Formula Weight516.2
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Molecular FormulaC17H17BrN3Na2O6P
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Purity>98% (HPLC)
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Solubility——
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SMILESO=c1c(=O)[nH]c2c(c(C(P(=O)(O)O)N[C@H](c3ccc(Br)cc3)C)ccc2)[nH]1
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Chemical Namesodium ((((S)-1-(4-bromophenyl)ethyl)amino)(2,3-dioxidoquinoxalin-5-yl)methyl)phosphonate hydrate .
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1.Auberson YP, et al. Bioorg Med Chem Lett. 2002 Apr 8;12(7):1099-102.
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