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SB269970 HCl

CAS No. 261901-57-9

SB269970 HCl( SB-269970A )

Catalog No. M17459 CAS No. 261901-57-9

SB269970 HCl, a hydrochloride salt form of SB-269970, is a 5-HT7 receptor antagonist (pKi of 8.3) and exhibits >50-fold selectivity against other receptors.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
1 mL x 10 mM in DMSO 149 In Stock
5MG 86 In Stock
10MG 135 In Stock
25MG 268 In Stock
50MG 389 In Stock
100MG 720 In Stock
200MG Get Quote In Stock
500MG Get Quote In Stock
1G Get Quote In Stock
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Biological Information

  • Product Name
    SB269970 HCl
  • Note
    Research use only, not for human use.
  • Brief Description
    SB269970 HCl, a hydrochloride salt form of SB-269970, is a 5-HT7 receptor antagonist (pKi of 8.3) and exhibits >50-fold selectivity against other receptors.
  • Description
    SB269970 HCl, a hydrochloride salt form of SB-269970, is a 5-HT7 receptor antagonist (pKi of 8.3) and exhibits >50-fold selectivity against other receptors.
  • In Vitro
    ——
  • In Vivo
    SB269970 hydrochloride (SB-269970A) (3-30 mg/kg; i.p.; once) significantly blocks amphetamine and ketamine-induced hyperactivity. Animal Model:Male C57BL6/J miceDosage:3, 10, 30 mg/kg Administration:Intraperitoneal injection; onceResult:Significantly blocked amphetamine and ketamine-induced hyperactivity.
  • Synonyms
    SB-269970A
  • Pathway
    Membrane Transporter/Ion Channel
  • Target
    TRP/TRPV Channel
  • Recptor
    5-HT7
  • Research Area
    Neurological Disease
  • Indication
    ——

Chemical Information

  • CAS Number
    261901-57-9
  • Formula Weight
    388.95
  • Molecular Formula
    C18H28N2O3S·HCl
  • Purity
    >98% (HPLC)
  • Solubility
    DMSO : ≥ 30 mg/mL; 77.13 mM
  • SMILES
    Cl.CC1CCN(CC[C@H]2CCCN2S(=O)(=O)c2cccc(O)c2)CC1
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Hagan JJ, et al. Br J Pharmacol, 2000, 130(3), 539-548.
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