R-IMPP( —— )

Catalog No. M17432 CAS No. 2133832-83-2

R-IMPP is an inhibitor of PCSK9 translation. R-IMPP stimulates uptake of LDL-C in hepatoma cells by increasing LDL-R levels, without altering levels of secreted transferrin.

Purity : >98% (HPLC)

COA

Datasheet

HNMR

HPLC

MSDS

Handing Instructions

Size	Price / USD	Stock	Quantity
1 mL x 10 mM in DMSO	69	Get Quote
2MG	51	Get Quote
5MG	81	Get Quote
10MG	143	Get Quote
25MG	296	Get Quote
50MG	516	Get Quote
100MG	742	Get Quote
200MG	Get Quote	Get Quote
500MG	Get Quote	Get Quote
1G	Get Quote	Get Quote

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Biological Information

Product Name

R-IMPP
Note

Research use only, not for human use.
Brief Description

R-IMPP is an inhibitor of PCSK9 translation. R-IMPP stimulates uptake of LDL-C in hepatoma cells by increasing LDL-R levels, without altering levels of secreted transferrin.
Description

R-IMPP is an inhibitor of PCSK9 translation. R-IMPP stimulates uptake of LDL-C in hepatoma cells by increasing LDL-R levels, without altering levels of secreted transferrin.
In Vitro

——
In Vivo

——
Synonyms

——
Pathway

Others
Target

Other Targets
Recptor

PCSK9
Research Area

Others-Field
Indication

——

Chemical Information

CAS Number

2133832-83-2
Formula Weight

389.21
Molecular Formula

C24H27N3O2
Purity

>98% (HPLC)
Solubility

DMSO : ≥ 41 mg/mL; 105.27 mM
SMILES

COC1=CC=C(CCC(N(C2=C(C=CC=C3)C3=CC=N2)[C@H]4CNCCC4)=O)C=C1
Chemical Name

——

Shipping & Storage Information

Storage

(-20℃)
Shipping

With Ice Pack
Stability

≥ 2 years

Reference

1. Petersen DN., et al. A Small-Molecule Anti-secretagogue of PCSK9 Targets the 80S Ribosome to Inhibit PCSK9 Protein Translation. Cell Chem Biol. 2016 Nov 17;23(11):1362-1371.

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