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GSK2200150A

CAS No. 1443138-53-1

GSK2200150A( GSK2200150A | GSK-2200150A | GSK 2200150A )

Catalog No. M17300 CAS No. 1443138-53-1

GSK2200150A, identified by high-throughput screening (HTS) campaign, is an anti-tuberculosis (TB) agent.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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Biological Information

  • Product Name
    GSK2200150A
  • Note
    Research use only, not for human use.
  • Brief Description
    GSK2200150A, identified by high-throughput screening (HTS) campaign, is an anti-tuberculosis (TB) agent.
  • Description
    GSK2200150A is an antimycobacterial agent against Mycobacterium tuberculosis and Mycobacterium bovis BCG.
  • In Vitro
    GSK2200150A is a novel antimycobacterial agent against Mycobacterium tuberculosis.The activities of GSK2200150A containing the spirocycle core are determined against the virulent M.tuberculosis strain (H37Rv) with MIC of 0.38 μM.
  • In Vivo
    ——
  • Synonyms
    GSK2200150A | GSK-2200150A | GSK 2200150A
  • Pathway
    JAK/STAT Signaling
  • Target
    Pim
  • Recptor
    Bacterial
  • Research Area
    Infection
  • Indication
    ——

Chemical Information

  • CAS Number
    1443138-53-1
  • Formula Weight
    357.47
  • Molecular Formula
    C20H23NO3S
  • Purity
    >98% (HPLC)
  • Solubility
    DMSO : ≥ 83.33 mg/mL. 233.11 mM
  • SMILES
    C4COC3(CCN(Cc1ccc2OCCOc2c1)CC3)c5ccsc45
  • Chemical Name
    1-[(2,3-Dihydro-1,4-benzodioxin-6-yl)methyl]-6',7'-dihydro-spiro[piperidine-4,4'-[4H]thieno[3,2-c]pyran]

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.?Badiola KA, et al. Efficient Synthesis and Anti-Tubercular Activity of a Series of Spirocycles: An Exercise in OpenScience. PLoS One. 2014 Dec 10;9(12):e111782.
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