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Saclofen

CAS No. 125464-42-8

Saclofen( Saclofen )

Catalog No. M17221 CAS No. 125464-42-8

Saclofen is a sulfonic analog of the inhibitory neurotransmitter γ-aminobutyric acid (GABA) that acts as a competitive antagonist of the GABAB receptor (IC50: 7.8 μM).

Purity : >98% (HPLC)

COA

Datasheet

HNMR

HPLC

MSDS

Handing Instructions

Size	Price / USD	Stock	Quantity
1 mL x 10 mM in DMSO	110	In Stock
5MG	116	In Stock
10MG	187	In Stock
25MG	359	In Stock
50MG	569	In Stock
100MG	889	In Stock
200MG	1200	In Stock
500MG	Get Quote	In Stock
1G	Get Quote	In Stock

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Biological Information

Product Name

Saclofen
Note

Research use only, not for human use.
Brief Description

Saclofen is a sulfonic analog of the inhibitory neurotransmitter γ-aminobutyric acid (GABA) that acts as a competitive antagonist of the GABAB receptor (IC50: 7.8 μM).
Description

Saclofen is a sulfonic analog of the inhibitory neurotransmitter γ-aminobutyric acid (GABA) that acts as a competitive antagonist of the GABAB receptor (IC50: 7.8 μM). This compound can be used to determine the functional roles for the GABAB receptor as a mediator of slow inhibitory postsynaptic potentials in the brain.
In Vitro

——
In Vivo

——
Synonyms

Saclofen
Pathway

Endocrinology/Hormones
Target

Androgen Receptor (AR)
Recptor

GABAB
Research Area

——
Indication

——

Chemical Information

CAS Number

125464-42-8
Formula Weight

249.71
Molecular Formula

C9H12ClNO3S
Purity

>98% (HPLC)
Solubility

In Vitro:?H2O : 10 mg/mL (40.05 mM)
SMILES

NCC(CS(O)(=O)=O)c1ccc(Cl)cc1
Chemical Name

3-Amino-2-(4-chlorophenyl)propane-1-sulfonic acid

Shipping & Storage Information

Storage

(-20℃)
Shipping

With Ice Pack
Stability

≥ 2 years

Reference

1.Drew C A, Johnston G A R, Kerr D I B, et al. Neuroscience letters, 1990, 113(1): 107-110.

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