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Leelamine hydrochloride
CAS No. 16496-99-4
Leelamine hydrochloride( Dehydroabietylamine )
Catalog No. M12521 CAS No. 16496-99-4
Leelamine hydrochloride (Dehydroabietylamine) is a novel inhibitor of androgen receptor (AR).
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
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| 100MG | Get Quote | Get Quote |
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| 200MG | Get Quote | Get Quote |
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| 500MG | Get Quote | Get Quote |
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| 1G | Get Quote | Get Quote |
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Biological Information
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Product NameLeelamine hydrochloride
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NoteResearch use only, not for human use.
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Brief DescriptionLeelamine hydrochloride (Dehydroabietylamine) is a novel inhibitor of androgen receptor (AR).
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DescriptionLeelamine hydrochloride (Dehydroabietylamine) is a novel inhibitor of androgen receptor (AR), inhibits castration-resistant prostate cancer cells; causes apoptosis and suppresses 22Rv1 xenograft growth in vivo; Leelamine mediates cancer cell death through inhibition of intracellular cholesterol transport.
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In Vitro——
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In Vivo——
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SynonymsDehydroabietylamine
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PathwayEndocrinology/Hormones
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TargetAndrogen Receptor (AR)
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RecptorAndrogen Receptor (AR)
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Research Area——
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Indication——
Chemical Information
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CAS Number16496-99-4
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Formula Weight321.933
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Molecular FormulaC20H32ClN
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Purity>98% (HPLC)
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SolubilityIn Vitro:?DMSO : 25 mg/mL (77.66 mM)
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SMILESCC(C)C1=CC2=C(C=C1)C3(CCCC(C3CC2)(C)CN)C.Cl
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Chemical Name1R,2,3,4,4aS,9,10,10aR-octahydro-1,4a-dimethyl-7-(1-methylethyl)-1-phenanthrenemethanamine, monohydrochloride
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Singh KB, et al. Mol Cancer Ther. 2018 Jul 20. pii: molcanther.0117.2018.
2. Gowda R, et al. Oncotarget. 2017 Apr 25;8(17):28260-28277.
3. Sehrawat A, et al. Mol Carcinog. 2017 Feb;56(2):337-348.
4. Kuzu OF, et al. Mol Cancer Ther. 2014 Jul;13(7):1690-703.
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