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GRL-079
CAS No. ——
GRL-079( GRL079 )
Catalog No. M17094 CAS No. ——
GRL-079 is a novel potent, nonpeptidic HIV-1 protease inhibitor with 2.5-30 nM.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
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Biological Information
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Product NameGRL-079
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NoteResearch use only, not for human use.
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Brief DescriptionGRL-079 is a novel potent, nonpeptidic HIV-1 protease inhibitor with 2.5-30 nM.
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DescriptionGRL-079 is a novel potent, nonpeptidic HIV-1 protease inhibitor with 2.5-30 nM against wild-type HIV-1NL4-3, 0.3-6.7 nM against HIV-2EHO, and 0.9-90 nM against laboratory-selected-PI-resistant HIV-1 and clinical HIV-1 variants resistant to multiple FDA-approved PIs (HIVMDR).
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In Vitro——
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In Vivo——
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SynonymsGRL079
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PathwayMicrobiology/Virology
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TargetHIV
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RecptorHIV
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Research Area——
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Indication——
Chemical Information
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CAS Number——
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Formula Weight703.914
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Molecular FormulaC34H49N5O7S2
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Purity>98% (HPLC)
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Solubility——
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SMILES——
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Chemical Name(3R,3aS,4S,7aS)-3-(ethylamino)hexahydro-4H-furo[2,3-b]pyran-4-yl ((2S,3R)-4-((2-(cyclopropylamino)-N-isobutylbenzo[d]thiazole)-6-sulfonamido)-3-hydroxy-1-phenylbutan-2-yl)carbamate
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Delino NS, et al. Antimicrob Agents Chemother. 2018 Feb 20. pii: AAC.02060-17.
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