Cart
sales@molnova.com
CAM4712
CAS No. ——
CAM4712( CAM 4712 | CAM-4712 )
Catalog No. M16980 CAS No. ——
CAM4712 (CAM-4712) is a potent and selective CK2α inhibitor with IC50 of 7 uM, exhibits cell growth inhibition in HCT116 cell line with IC50 of 10 uM.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 100MG | Get Quote | Get Quote |
|
| 200MG | Get Quote | Get Quote |
|
| 500MG | Get Quote | Get Quote |
|
| 1G | Get Quote | Get Quote |
|
Biological Information
-
Product NameCAM4712
-
NoteResearch use only, not for human use.
-
Brief DescriptionCAM4712 (CAM-4712) is a potent and selective CK2α inhibitor with IC50 of 7 uM, exhibits cell growth inhibition in HCT116 cell line with IC50 of 10 uM.
-
DescriptionCAM4712 (CAM-4712) is a potent and selective CK2α inhibitor with IC50 of 7 uM, exhibits cell growth inhibition in HCT116 cell line with IC50 of 10 uM; displays good selectivity against the 20 closely related CMGC kinases; inhibits CK2α dependent phosphorylation of Ser129 of Akt1 in cellular assays, CAM4066 has numerous advantages over the previously reported CAM4066.
-
In Vitro——
-
In Vivo——
-
SynonymsCAM 4712 | CAM-4712
-
PathwayMetabolic Enzyme/Protease
-
TargetCasein Kinase
-
RecptorCasein Kinase
-
Research Area——
-
Indication——
Chemical Information
-
CAS Number——
-
Formula Weight425.376
-
Molecular FormulaC24H24Cl2N3+
-
Purity>98% (HPLC)
-
Solubility——
-
SMILES——
-
Chemical Name2-(2-(((2,6-dichloro-2'-ethyl-[1,1'-biphenyl]-4-yl)methyl)amino)ethyl)-1H-benzo[d]imidazol-3-ium
Shipping & Storage Information
-
Storage(-20℃)
-
ShippingWith Ice Pack
-
Stability≥ 2 years
Reference
1. Iegre J, et al. Chem Sci. 2018 Feb 20;9(11):3041-3049.
molnova catalog
related products
-
(R)-DRF053 dihydroch...
(R)-DRF053 dihydrochloride (DRF053)?is a potent, cell-permeable, dual CK1/CDK inhibitor with IC50 of 14 nM, 220 nM and 80 nM for CK1, CDK5/p25 and CDK1/cyclin B, respectively.
-
VU-WS113
VU-WS113 is a potent inhibitor of Wnt signaling with EC50 of 80 nM that selectively potentiates CK1α kinase activity.
-
Casein kinase 1δ-IN-...
Casein kinase 1δ-IN-8 is an inhibitor of casein kinase 1δ and is used to treat neurodegenerative diseases such as Alzheimer's disease type.
