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SGI-7079
CAS No. 1239875-86-5
SGI-7079( SGI-7079 | SGI 7079 | SGI7079 )
Catalog No. M17214 CAS No. 1239875-86-5
SGI-7079 is a new selective Axl inhibitor. SGI-7079 can be a dose-dependent manner inhibited growth of tumors.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 1 mL x 10 mM in DMSO | 59 | In Stock |
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| 2MG | 33 | In Stock |
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| 5MG | 53 | In Stock |
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| 10MG | 93 | In Stock |
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| 25MG | 188 | In Stock |
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| 50MG | 237 | In Stock |
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| 100MG | 346 | In Stock |
|
| 200MG | Get Quote | In Stock |
|
| 500MG | 808 | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
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Product NameSGI-7079
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NoteResearch use only, not for human use.
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Brief DescriptionSGI-7079 is a new selective Axl inhibitor. SGI-7079 can be a dose-dependent manner inhibited growth of tumors.
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DescriptionSGI-7079 is a potent and selective Axl inhibitor with potential anticancer activity. SGI-7079 effectively inhibited Axl activation in the presence of exogenous Gas6 ligand. SGI-7079 inhibited tumor growth in a dose dependent manner. Axl is a potential therapeutic target for overcoming EGFR inhibitor resistance.
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In Vitro——
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In Vivo——
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SynonymsSGI-7079 | SGI 7079 | SGI7079
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PathwayMetabolic Enzyme/Protease
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TargetCasein Kinase
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RecptorMet| RET| FLT3| Yes| AXL| Mer
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Research AreaCancer
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Indication——
Chemical Information
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CAS Number1239875-86-5
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Formula Weight455.53
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Molecular FormulaC26H26FN7
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Purity>98% (HPLC)
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SolubilityDMSO : ≥ 34 mg/mL. 74.64 mM
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SMILESCN1CCN(CC1)c1ccc(Nc2nc3c(c(C)c[nH]3)c(n2)c2cc(CC#N)ccc2)cc1F
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Chemical Name2-(3-(2-((3-fluoro-4-(4-methylpiperazin-1-yl)phenyl)amino)-5-methyl-7H-pyrrolo[2,3-d]pyrimidin-4-yl)phenyl)acetonitrile
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Myers SH, et al. J Med Chem. 2016, 59(8):3593-608.
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