Cart
sales@molnova.com
PCI-32765 racemate
CAS No. 936563-87-0
PCI-32765 racemate( Ibrutinib Racemate | PCI32765 Racemate | PCI 32765 Racemate )
Catalog No. M16704 CAS No. 936563-87-0
A potent a+M7692nd highly selective Btk inhibitor with IC50 of 0.5 nM.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 50MG | 235 | In Stock |
|
| 100MG | Get Quote | In Stock |
|
| 200MG | Get Quote | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
-
Product NamePCI-32765 racemate
-
NoteResearch use only, not for human use.
-
Brief DescriptionA potent a+M7692nd highly selective Btk inhibitor with IC50 of 0.5 nM.
-
DescriptionA potent a+M7692nd highly selective Btk inhibitor with IC50 of 0.5 nM; modestly potent to Bmx, CSK, FGR, BRK, HCK, less potent to EGFR, Yes, ErbB2, JAK3, etc.Blood Cancer Approved.
-
In Vitro——
-
In Vivo——
-
SynonymsIbrutinib Racemate | PCI32765 Racemate | PCI 32765 Racemate
-
PathwayTyrosine Kinase
-
TargetBTK
-
RecptorBTK
-
Research AreaCancer
-
IndicationBlood cancer
Chemical Information
-
CAS Number936563-87-0
-
Formula Weight440.4971
-
Molecular FormulaC25H24N6O2
-
Purity>98% (HPLC)
-
Solubility10 mM in DMSO
-
SMILESC=CC(=O)N1CCCC(C1)N2C3=NC=NC(=C3C(=N2)C4=CC=C(C=C4)OC5=CC=CC=C5)N
-
Chemical Name2-Propen-1-one, 1-[3-[4-amino-3-(4-phenoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl]-1-piperidinyl]-
Shipping & Storage Information
-
Storage(-20℃)
-
ShippingWith Ice Pack
-
Stability≥ 2 years
Reference
1. Honigberg LA, et al. Proc Natl Acad Sci U S A. 2010 Jul 20;107(29):13075-80.
2. Herman SE, et al. Blood. 2014 May 22;123(21):3286-95.
3. Kohrt HE, et al. Blood. 2014 Mar 20;123(12):1957-60.
molnova catalog
related products
-
Ibrutinib deacryloyl...
Ibrutinib deacryloylpiperidine is a highly selective Bruton’s tyrosine kinase (BTK) irreversible inhibitor with an IC50 of 0.5 nM.
-
CGI-1746
CGI-1746 is a potent, highly selective, second-generation BTK inhibitor with IC50 of 1.9 nM.
-
AVL-292
AVL-292 (Spebrutinib, CC-292) is a highly selective, covalent Btk inhibitor with IC50 of <1 nM; also less potently inhibits Yes, c-Src, Brk, Lyn, and Fyn with IC50s of 723 nM, 1.729 uM, 2.43 uM, 4.4 uM, and 7.15 uM, rspectively.
