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KS-99
CAS No. 1344698-28-7
KS-99( KS99 | KS 99 )
Catalog No. M11378 CAS No. 1344698-28-7
KS-99 (KS99) is a novel dual inhibitor of BTK and tubulin polymerization.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 5MG | 873 | Get Quote |
|
| 50MG | 1782 | Get Quote |
|
| 100MG | 2250 | Get Quote |
|
| 200MG | Get Quote | Get Quote |
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| 500MG | Get Quote | Get Quote |
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| 1G | Get Quote | Get Quote |
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Biological Information
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Product NameKS-99
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NoteResearch use only, not for human use.
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Brief DescriptionKS-99 (KS99) is a novel dual inhibitor of BTK and tubulin polymerization.
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DescriptionKS-99 (KS99) is a novel dual inhibitor of BTK and tubulin polymerization; interacts directly with the catalytic domain of BTK and inhibits phosphorylation at the Y223 residue and kinase activities; reduces the cell viability of MM and CD138+ cells (IC50=0.5-1 uM); inhibits the in vivo tumor growth of MM cells through the inhibition of BTK and tubulin.
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In Vitro——
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In Vivo——
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SynonymsKS99 | KS 99
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PathwayTyrosine Kinase
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TargetBTK
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RecptorBTK
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Research Area——
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Indication——
Chemical Information
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CAS Number1344698-28-7
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Formula Weight466.147
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Molecular FormulaC17H10Br2N2O2S
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Purity>98% (HPLC)
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Solubility——
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SMILESO=C1N(CC2=CC=C(CSC#N)C=C2)C3=C(C=C(Br)C=C3Br)C1=O
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Chemical Name5,7-dibromo-1-(4-(thiocyanatomethyl)benzyl)indoline-2,3-dione
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Pandey MK, et al. Exp Hematol. 2017 Jun 22. pii: S0301-472X(17)30233-3.
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