Azilsartan medoxomil monopotassium
CAS No. 863031-24-7
Azilsartan medoxomil monopotassium( TAK-491 )
Catalog No. M16247 CAS No. 863031-24-7
An orally administered angiotensin II receptor type 1 antagonist with IC50 of 0.62 nM.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
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Biological Information
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Product NameAzilsartan medoxomil monopotassium
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NoteResearch use only, not for human use.
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Brief DescriptionAn orally administered angiotensin II receptor type 1 antagonist with IC50 of 0.62 nM.
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DescriptionAn orally administered angiotensin II receptor type 1 antagonist with IC50 of 0.62 nM, which used in the treatment of adults with essential hypertension. Hypertension Approved.
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In Vitro——
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In Vivo——
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SynonymsTAK-491
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PathwayGPCR/G Protein
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TargetAngiotensin Receptor
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RecptorAngiotensin Receptor
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Research AreaCardiovascular Disease
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IndicationHypertension
Chemical Information
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CAS Number863031-24-7
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Formula Weight606.6239
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Molecular FormulaC30H23KN4O8
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Purity>98% (HPLC)
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Solubility10 mM in DMSO
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SMILESCCOC1=NC2=CC=CC(=C2N1CC3=CC=C(C=C3)C4=CC=CC=C4C5=NC(=O)O[N-]5)C(=O)OCC6=C(OC(=O)O6)C.[K+]
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Chemical Name1H-Benzimidazole-7-carboxylic acid, 1-[[2'-(2,5-dihydro-5-oxo-1,2,4-oxadiazol-3-yl)[1,1'-biphenyl]-4-yl]methyl]-2-ethoxy-, (5-methyl-2-oxo-1,3-dioxol-4-yl)methyl ester, potassium salt (1:1)
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
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Norleual
Angiotensin IV analog. Highly potent HGF/c-MET inhibitor (IC50 = 3 pM). Inhibits HGF-induced MDCK cell proliferation and invasion in vitro. Also AT4 receptor antagonist; disrupts LTP stabilization. Antiangiogenic.
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C-Type Natriuretic P...
CNP, a member of the natriuretic peptide family, was first identified in porcine brain and later found in other mammals as well as non-mammals. Processing of the CNP precursor gives rise to CNP-22 and its N-terminally elongated form, CNP-53. The CNPs share considerable sequence homology with ANP and BNP within the disulfide loop and exert similar pharmacological actions, although with different relative potencies.
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Saralasin
Competitive non-selective angiotensin II antagonist.
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