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Naronapride
CAS No. 860174-12-5
Naronapride( ATI-7505 )
Catalog No. M16233 CAS No. 860174-12-5
Naronapride (ATI-7505) is a potent, selective and orally active 5-HT4 receptor agonist with Ki of 1.4 nM.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 5MG | 682 | In Stock |
|
| 50MG | 2507 | In Stock |
|
| 100MG | 3168 | In Stock |
|
| 200MG | Get Quote | In Stock |
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| 500MG | Get Quote | In Stock |
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| 1G | Get Quote | In Stock |
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Biological Information
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Product NameNaronapride
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NoteResearch use only, not for human use.
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Brief DescriptionNaronapride (ATI-7505) is a potent, selective and orally active 5-HT4 receptor agonist with Ki of 1.4 nM.
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DescriptionNaronapride (ATI-7505) is a potent, selective and orally active 5-HT4 receptor agonist with Ki of 1.4 nM; displays negligible affinity for Kv11.1 channels (Ki=24,500 nM), and no effect on cardiac repolarization; shows potential for treatment of gastrointestinal motility disorders.Other Indication Phase 2 Clinical.
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In Vitro——
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In Vivo——
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SynonymsATI-7505
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PathwayGPCR/G Protein
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Target5-HT Receptor
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Recptor5-HT Receptor
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Research AreaOther Indications
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IndicationOther Disease
Chemical Information
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CAS Number860174-12-5
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Formula Weight537.098
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Molecular FormulaC27H41ClN4O5
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Purity>98% (HPLC)
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SolubilityIn Vitro:?DMSO : 100 mg/mL (186.19 mM)
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SMILESO=C(O[C@H]1CN2CCC1CC2)CCCCCN3C[C@H](OC)[C@H](NC(C4=CC(Cl)=C(N)C=C4OC)=O)CC3
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Chemical Name[(3R)-1-azabicyclo[2.2.2]octan-3-yl] 6-[(3S,4R)-4-[(4-amino-5-chloro-2-methoxybenzoyl)amino]-3-methoxypiperidin-1-yl]hexanoate
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Manabe N, et al. Expert Opin Investig Drugs. 2010 Jun;19(6):765-75.
2. Bowersox SS, et al. Drug Metab Dispos. 2011 Jul;39(7):1170-80.
3. Hoffman JM, et al. Gastroenterology. 2012 Apr;142(4):844-854.e4.
4. Camilleri M, et al. Neurogastroenterol Motil. 2007 Jan;19(1):30-8.
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