Diammonium Glycyrrhizinate( —— )

Catalog No. M15969 CAS No. 79165-06-3

COA

Datasheet

HNMR

HPLC

MSDS

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Product Name

Diammonium Glycyrrhizinate
Note

Research use only, not for human use.
Brief Description

Diammonium glycyrrhizinate is a widely used anti-inflammatory agent isolated from the licorice root.
Description

Diammonium glycyrrhizinate is a widely used anti-inflammatory agent isolated from the licorice root. It is metabolized to glycyrrhetinic acid, which inhibits 11-beta-hydroxysteroid dehydrogenases and other enzymes involved in the metabolism of corticosteroids. Therefore, glycyrrhizic acid, which is the main and sweet component of licorice, has been investigated for its ability to cause hypermineralocorticoidism with sodium retention and potassium loss, edema, increased blood pressure, as well as depression of the renin-angiotensin-aldosterone system.
In Vitro

——
In Vivo

——
Synonyms

——
Pathway

Metabolic Enzyme/Protease
Target

Dehydrogenase
Recptor

11-beta-hydroxysteroid dehydrogenase
Research Area

Other Indications
Indication

——

CAS Number

79165-06-3
Formula Weight

857
Molecular Formula

C42H62O16·2H3N
Purity

>98% (HPLC)
Solubility

Soluble in Water
SMILES

C[C@]12CC[C@](C[C@H]1C3=CC(=O)[C@@H]4[C@]5(CC[C@@H](C([C@@H]5CC[C@]4([C@@]3(CC2)C)C)(C)C)O[C@@H]6[C@@H]([C@H]([C@@H]([C@H](O6)C(=O)O)O)O)O[C@H]7[C@@H]([C@H]([C@@H]([C@H](O7)C(=O)O)O)O)O)C)(C)C(=O)O.N.N
Chemical Name

——

1. Jin J, et al. Food Chem Toxicol. 2014 Nov;73:95-104.

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