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SUVN-502
CAS No. 701205-60-9
SUVN-502( SUVN502 | Masupirdine )
Catalog No. M15690 CAS No. 701205-60-9
SUVN-502 (SUVN502, Masupirdine) is a potent, selective, brain penetrant and orally active 5-HT6 receptor antagonist with Ki of 2.04 nM.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 5MG | 873 | Get Quote |
|
| 50MG | 1782 | Get Quote |
|
| 100MG | 2250 | Get Quote |
|
| 200MG | Get Quote | Get Quote |
|
| 500MG | Get Quote | Get Quote |
|
| 1G | Get Quote | Get Quote |
|
Biological Information
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Product NameSUVN-502
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NoteResearch use only, not for human use.
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Brief DescriptionSUVN-502 (SUVN502, Masupirdine) is a potent, selective, brain penetrant and orally active 5-HT6 receptor antagonist with Ki of 2.04 nM.
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DescriptionSUVN-502 (SUVN502, Masupirdine) is a potent, selective, brain penetrant and orally active 5-HT6 receptor antagonist with Ki of 2.04 nM; shows high selectivity over 5-HT2A receptor and other 100 target sites; produces synergistic effects in extracellular levels of acetylcholine in the ventral hippocampus combined with donepezil and memantine; shows potential for treatment of Alzheimer's disease.Alzheimer Disease Phase 2 Clinical.
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In Vitro——
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In Vivo——
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SynonymsSUVN502 | Masupirdine
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PathwayGPCR/G Protein
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Target5-HT Receptor
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Recptor5-HT Receptor
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Research AreaNeurological Disease
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IndicationAlzheimer Disease
Chemical Information
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CAS Number701205-60-9
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Formula Weight478.405
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Molecular FormulaC21H24BrN3O3S
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Purity>98% (HPLC)
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Solubility——
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SMILESCN1CCN(CC1)CC2=CN(C3=C2C=C(C=C3)OC)S(=O)(=O)C4=CC=CC=C4Br
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Chemical Name1-((2-bromophenyl)sulfonyl)-5-methoxy-3-((4-methylpiperazin-1-yl)methyl)-1H-indole
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Nirogi R, et al. J Med Chem. 2017 Mar 9;60(5):1843-1859.
2. Nirogi R, et al. J Pharm Biomed Anal. 2017 Apr 14;145:423-430.
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