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WAY-100635 maleate (b)
CAS No. 634908-75-1
WAY-100635 maleate (b)( WAY 100635 maleate salt | WAY100635 maleate salt )
Catalog No. M15399 CAS No. 634908-75-1
WAY-100635 is a potent and selective 5-HT1A receptor antagonist; also acts as potent full agonist at the D4 receptor.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 2MG | 34 | In Stock |
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| 5MG | 55 | In Stock |
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| 10MG | 86 | In Stock |
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| 25MG | 146 | In Stock |
|
| 50MG | 214 | In Stock |
|
| 100MG | 317 | In Stock |
|
| 500MG | 764 | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
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Product NameWAY-100635 maleate (b)
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NoteResearch use only, not for human use.
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Brief DescriptionWAY-100635 is a potent and selective 5-HT1A receptor antagonist; also acts as potent full agonist at the D4 receptor.
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DescriptionWAY-100635 is a potent and selective 5-HT1A receptor antagonist; also acts as potent full agonist at the D4 receptor; completely prevents not only the hyperpolarization, with an IC50 of 1.3 nM, but also the decrease in membrane input resistance produced by 5-HT and 5-carboxamidotryptamine with IC50 of 22.5 μM and 50 nM, respectively.Anxiety Phase 1 Discontinued.
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In Vitro——
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In Vivo——
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SynonymsWAY 100635 maleate salt | WAY100635 maleate salt
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PathwayGPCR/G Protein
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Target5-HT Receptor
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Recptor5-HT1A
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Research AreaNeurological Disease
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IndicationAnxiety
Chemical Information
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CAS Number634908-75-1
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Formula Weight538.6352
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Molecular FormulaC29H38N4O6
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Purity>98% (HPLC)
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SolubilityDMSO: ≥ 34 mg/mL
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SMILESCOC1=CC=CC=C1N2CCN(CC2)CCN(C3=CC=CC=N3)C(=O)C4CCCCC4.C(=CC(=O)O)C(=O)O
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Chemical NameCyclohexanecarboxamide, N-[2-[4-(2-methoxyphenyl)-1-piperazinyl]ethyl]-N-2-pyridinyl-, (2Z)-2-butenedioate (9CI)
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Corradetti R, et al. J Pharmacol Exp Ther. 1996 Aug;278(2):679-88.
2. Fornal CA, et al. J Pharmacol Exp Ther. 1996 Aug;278(2):752-62.
3. García G, et al. Eur J Med Chem. 2014 Oct 6;85:795-806.
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