Agipnon

Research use only, not for human use.

Bemegride is a central nervous system stimulant and antidote for barbiturate poisoning.

Bemegride is a central nervous system stimulant and antidote for barbiturate poisoning.(In Vitro):Bemegride has an antagonistic action on the GABAA receptor, suppressing both GABA- and pentobarbitone-evoked whole-cell currents to similar extents. Long-term oral administration to the rat of barbitone, alone or together with the analeptics bemegride or pentylenetetrazol, show that the intensity of the withdrawal syndrome generally parallels the degree of associated CNS depression.

Bemegride has an antagonistic action on the GABAA receptor, suppressing both GABA- and pentobarbitone-evoked whole-cell currents to similar extents. Long-term oral administration to the rat of barbitone, alone or together with the analeptics bemegride or pentylenetetrazol, show that the intensity of the withdrawal syndrome generally parallels the degree of associated CNS depression.

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Bemegride | Antibarbi | Agipnon | Ahypnon | Eukraton | Malysol | Mikedimide | Zentraleptin

Membrane Transporter/Ion Channel

GAT

GABAR

Neurological Disease

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64-65-3

155.19

C8H13NO2

>98% (HPLC)

Ethanol: 31 mg/mL (199.75 mM); DMSO: 31 mg/mL (199.75 mM)

O=C(CC(C)(CC)C1)NC1=O

2,6-Piperidinedione, 4-ethyl-4-methyl-

(-20℃)

With Ice Pack

≥ 2 years