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DA-6886

CAS No. 1645260-76-9

DA-6886( —— )

Catalog No. M34220 CAS No. 1645260-76-9

DA-6886 is an agonist 5-Hydroxytryptamine receptor 4 (5-HT4). DA-6886 induced relaxation of the rat oesophagus preparation in a 5-HT4 receptor antagonist-sensitive manner.

Purity : >98% (HPLC)

COA

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HPLC

MSDS

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Biological Information

Product Name

DA-6886
Note

Research use only, not for human use.
Brief Description

DA-6886 is an agonist 5-Hydroxytryptamine receptor 4 (5-HT4). DA-6886 induced relaxation of the rat oesophagus preparation in a 5-HT4 receptor antagonist-sensitive manner.
Description

DA-6886 is an agonist 5-Hydroxytryptamine receptor 4 (5-HT4). DA-6886 induced relaxation of the rat oesophagus preparation in a 5-HT4 receptor antagonist-sensitive manner. The evaluation of DA-6886 in CHO cells expressing hERG channels revealed that it inhibited hERG channel current with an pIC50 value of 4.3, indicating that the compound was 1000-fold more selective for the 5-HT4 receptor over hERG channels.
In Vitro

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In Vivo

——
Synonyms

——
Pathway

GPCR/G Protein
Target

5-HT Receptor
Recptor

5-HT Receptor
Research Area

——
Indication

——

Chemical Information

CAS Number

1645260-76-9
Formula Weight

443.37
Molecular Formula

C19H28Cl2N6O2
Purity

>98% (HPLC)
Solubility

——
SMILES

Cl.O=C(NCC1CCN(CCCN2N=NC=C2)CC1)C3=CC(Cl)=C(N)C=C3OC
Chemical Name

——

Shipping & Storage Information

Storage

(-20℃)
Shipping

With Ice Pack
Stability

≥ 2 years

Reference

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