Cart
sales@molnova.com
Sodium Cridanimod
CAS No. 58880-43-6
Sodium Cridanimod( XBIO-101 | XBIO101 | Cridanimod sodium )
Catalog No. M15173 CAS No. 58880-43-6
A potent type I interferon (IFN) inducer that directly binds to STING and triggers a strong antiviral response through the TBK1/IRF3 route.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 50MG | 1221 | Get Quote |
|
| 100MG | Get Quote | Get Quote |
|
| 200MG | Get Quote | Get Quote |
|
| 500MG | Get Quote | Get Quote |
|
| 1G | Get Quote | Get Quote |
|
Biological Information
-
Product NameSodium Cridanimod
-
NoteResearch use only, not for human use.
-
Brief DescriptionA potent type I interferon (IFN) inducer that directly binds to STING and triggers a strong antiviral response through the TBK1/IRF3 route.
-
DescriptionA potent type I interferon (IFN) inducer that directly binds to STING and triggers a strong antiviral response through the TBK1/IRF3 route; displays extraordinary activity in phosphorylating IRF3 in the murine system; also increases progesterone receptor (PrR) expression in endometrial tissue.Ovarian Cancer Phase 2 Clinical.
-
In Vitro——
-
In Vivo——
-
SynonymsXBIO-101 | XBIO101 | Cridanimod sodium
-
PathwayImmunology/Inflammation
-
TargetSTING
-
RecptorSTING
-
Research AreaCancer
-
IndicationOvarian Cancer
Chemical Information
-
CAS Number58880-43-6
-
Formula Weight276.247
-
Molecular FormulaC15H11NNaO3
-
Purity>98% (HPLC)
-
Solubility——
-
SMILESC1=CC=C2C(=C1)C(=O)C3=CC=CC=C3N2CC(=O)[O-].[Na+]
-
Chemical Name2-(9-oxoacridin-10(9H)-yl)acetic acid, sodium salt
Shipping & Storage Information
-
Storage(-20℃)
-
ShippingWith Ice Pack
-
Stability≥ 2 years
Reference
1. Cavlar T, et al. EMBO J. 2013 May 15;32(10):1440-50.
2. Zhang H, et al. Sci Rep. 2015 Dec 16;5:18035.
molnova catalog
related products
-
ADU-S100 ammonium sa...
ADU-S100 ammonium salt is an activator of stimulator of interferon genes (STING).
-
SN-008
SN-008 is a less active analog SN-011 which is a STING antagonist. SN-008 can be used as a negative control.
-
C-171
C-171 is an inhibitor of stimulator of interferon genes (STING).?It binds to STING, inhibits its palmitoylation, and prevents the recruitment and phosphorylation of TBK1.
