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NU-7163
CAS No. 503468-03-9
NU-7163( NU7163 | NU 7163 )
Catalog No. M14706 CAS No. 503468-03-9
A poten and selective, ATP-competitive DNA-PK inhibitor with IC50 of 0.19 uM, Ki of 24 nM.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 5MG | 873 | Get Quote |
|
| 50MG | 1782 | Get Quote |
|
| 100MG | 2250 | Get Quote |
|
| 200MG | Get Quote | Get Quote |
|
| 500MG | Get Quote | Get Quote |
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| 1G | Get Quote | Get Quote |
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Biological Information
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Product NameNU-7163
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NoteResearch use only, not for human use.
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Brief DescriptionA poten and selective, ATP-competitive DNA-PK inhibitor with IC50 of 0.19 uM, Ki of 24 nM.
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DescriptionA poten and selective, ATP-competitive DNA-PK inhibitor with IC50 of 0.19 uM, Ki of 24 nM; exhibits selectivity for DNA-PK versus related enzymes ATM, ATR, mTOR, and p110α; sensitizes the HeLa cells to the cytotoxic effects of ionizing radiation in vitro.
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In Vitro——
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In Vivo——
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SynonymsNU7163 | NU 7163
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PathwayCell Cycle/DNA Damage
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TargetDNA-PK
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RecptorDNA-PK
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Research Area——
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Indication——
Chemical Information
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CAS Number503468-03-9
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Formula Weight295.338
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Molecular FormulaC18H17NO3
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Purity>98% (HPLC)
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Solubility——
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SMILESO=C1C=C(N2CC(C)OCC2)OC3=C1C=CC4=CC=CC=C43
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Chemical Name2-(2-methylmorpholino)-4H-benzo[h]chromen-4-one
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Griffin RJ, et al. J Med Chem. 2005 Jan 27;48(2):569-85.
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