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SU-11752
CAS No. 688036-19-3
SU-11752( SU11752 )
Catalog No. M15627 CAS No. 688036-19-3
SU-11752 is a potent, selective inhibitor of DNA-PK.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 5MG | 1053 | Get Quote |
|
| 50MG | 2142 | Get Quote |
|
| 100MG | 2790 | Get Quote |
|
| 200MG | Get Quote | Get Quote |
|
| 500MG | Get Quote | Get Quote |
|
| 1G | Get Quote | Get Quote |
|
Biological Information
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Product NameSU-11752
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NoteResearch use only, not for human use.
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Brief DescriptionSU-11752 is a potent, selective inhibitor of DNA-PK.
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DescriptionSU-11752 is a potent, selective inhibitor of DNA-PK, >500-fold selectivity over PI3Kγ, inhibits DNA double-strand break repair in cells and sensitizs ionizing radiation in cancer cells.
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In Vitro——
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In Vivo——
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SynonymsSU11752
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PathwayCell Cycle/DNA Damage
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TargetDNA-PK
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RecptorDNA-PK
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Research Area——
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Indication——
Chemical Information
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CAS Number688036-19-3
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Formula Weight493.57
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Molecular FormulaC26H27N3O5S
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Purity>98% (HPLC)
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Solubility——
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SMILESO=C(O)CCC1=C(CC)NC(/C=C2C(NC3=C\2C=C(S(=O)(NC4=CC=CC=C4)=O)C=C3)=O)=C1CC
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Chemical Name5-[[1,2-Dihydro-2-oxo-5-[(phenylamino)sulfonyl]-3H-indol-3-ylidene]methyl]-2,4-diethyl-1H-pyrrole-3-propanoic acid
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Ismail IH, et al. Oncogene. 2004 Jan 29;23(4):873-82.
2. Harnor SJ, et al. ChemMedChem. 2017 Jun 21;12(12):895-900.
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