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KU-57788
CAS No. 503468-95-9
KU-57788( KU 57788 | NU-7441 | KU57788 | NU7441 | NU 7441 )
Catalog No. M14707 CAS No. 503468-95-9
A highly potent and selective DNA-PK inhibitor (IC50=14 nM).
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 2MG | 31 | In Stock |
|
| 5MG | 49 | In Stock |
|
| 10MG | 81 | In Stock |
|
| 25MG | 158 | In Stock |
|
| 50MG | 267 | In Stock |
|
| 100MG | 372 | In Stock |
|
| 500MG | 881 | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
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Product NameKU-57788
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NoteResearch use only, not for human use.
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Brief DescriptionA highly potent and selective DNA-PK inhibitor (IC50=14 nM).
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DescriptionA highly potent and selective DNA-PK inhibitor (IC50=14 nM); also modestly inhibits BRD4 and BRDT with IC50 of 1 uM and 3.5 uM respectively; also stimulates Cas9-mediated genome editing.
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In Vitro——
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In Vivo——
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SynonymsKU 57788 | NU-7441 | KU57788 | NU7441 | NU 7441
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PathwayCell Cycle/DNA Damage
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TargetDNA-PK
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RecptorATM|ATR|DNA-PK|mTOR|PI3K
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Research AreaCancer
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Indication——
Chemical Information
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CAS Number503468-95-9
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Formula Weight413.4883
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Molecular FormulaC25H19NO3S
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Purity>98% (HPLC)
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Solubility10 mM in DMSO
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SMILESO=C1C=C(N2CCOCC2)OC3=C(C4=C5C(C6=CC=CC=C6S5)=CC=C4)C=CC=C13
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Chemical Name4H-1-Benzopyran-4-one, 8-(4-dibenzothienyl)-2-(4-morpholinyl)-
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Leahy JJ, et al. Bioorg Med Chem Lett. 2004 Dec 20;14(24):6083-7.
2. Robert F, et al. Genome Med. 2015 Aug 27;7:93.
3. Ember SW, et al. ACS Chem Biol. 2014 May 16;9(5):1160-71.
molnova catalog
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