Vitamin D2
CAS No. 50-14-6
Vitamin D2( Calciferol | Ergocalciferol | Fortodyl | Infron | Mulsiferol | NSC 62792 | Radiostol | Uvesterol D )
Catalog No. M14687 CAS No. 50-14-6
Vitamin D2 has a strong inhibitory effect against bladder tumor promotion by sodium saccharin and induces cell differentiation in leukemia cells.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
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Biological Information
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Product NameVitamin D2
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NoteResearch use only, not for human use.
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Brief DescriptionVitamin D2 has a strong inhibitory effect against bladder tumor promotion by sodium saccharin and induces cell differentiation in leukemia cells.
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DescriptionVitamin D2 has a strong inhibitory effect against bladder tumor promotion by sodium saccharin and induces cell differentiation in leukemia cells. Vitamin D2 is an inhibitor of DNA Polymerase.(In Vivo):At sacrifice, after 5 weeks of treatment, chickens receiving omeprazole alone or omeprazole in combination with either restricted food intake or Ergocalciferol weighed 15-25% less (P < 0.01) than chickens given vehicle or receiving reduced amount of food.Combined treatments of fasting and ergocalciferol show more deleterious effects on growth than fasting only or ergocalciferol only and induced face anomalies.
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In Vitro——
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In VivoAt sacrifice, after 5 weeks of treatment, chickens receiving omeprazole alone or omeprazole in combination with either restricted food intake or Ergocalciferol weighed 15-25% less (P < 0.01) than chickens given vehicle or receiving reduced amount of food.Combined treatments of fasting and ergocalciferol show more deleterious effects on growth than fasting only or ergocalciferol only and induced face anomalies. Animal Model:83 chickens (White Leghorn), weighing 318 ± 9 g.Dosage:250,000 IU/kg Administration:S.C. once daily.Result:Induced a long-lasting hypercalcemia in rat and mice and suppresses the expression of PTH mRNA in the rat.
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SynonymsCalciferol | Ergocalciferol | Fortodyl | Infron | Mulsiferol | NSC 62792 | Radiostol | Uvesterol D
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PathwayCell Cycle/DNA Damage
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TargetDNA/RNA Synthesis
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RecptorDNA polymerase| VD3
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Research AreaMetabolic Disease
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Indication——
Chemical Information
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CAS Number50-14-6
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Formula Weight396.65
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Molecular FormulaC28H44O
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Purity>98% (HPLC)
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SolubilityEthanol: 80 mg/mL (201.68 mM); DMSO: 20 mg/mL (50.42 mM)
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SMILESO[C@@H]1C/C(C(CC1)=C)=C/C=C2[C@]3([H])CC[C@H]([C@H](C)/C=C/[C@H](C)C(C)C)[C@@]3(C)CCC/2
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Chemical Name(S,Z)-3-(2-((1R,3aS,7aR,E)-1-((2R,5R,E)-5,6-dimethylhept-3-en-2-yl)-7a-methyloctahydro-4H-inden-4-ylidene)ethylidene)-4-methylenecyclohexan-1-ol
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1.Mizushina Y, et al. J Pharmacol Sci. 2003 Jul;92(3):283-90.
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