2-O-(2-Methoxyethyl)adenosine
CAS No. 168427-74-5
2-O-(2-Methoxyethyl)adenosine( —— )
Catalog No. M37874 CAS No. 168427-74-5
2'-O-(2-Methoxyethyl)adenosine is a nucleoside analog used to improve RNA target affinity and nuclease resistance of therapeutic oligonucleotides in preclin.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 1 mL x 10 mM in DMSO | 37 | In Stock |
|
| 50MG | 28 | In Stock |
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| 100MG | 39 | In Stock |
|
| 200MG | Get Quote | In Stock |
|
| 500MG | 100 | In Stock |
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| 1G | 151 | In Stock |
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Biological Information
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Product Name2-O-(2-Methoxyethyl)adenosine
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NoteResearch use only, not for human use.
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Brief Description2'-O-(2-Methoxyethyl)adenosine is a nucleoside analog used to improve RNA target affinity and nuclease resistance of therapeutic oligonucleotides in preclin.
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Description2′-O-(2-Methoxyethyl)adenosine is a compound can be used in the synthesis of oligonucleotides.
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In Vitro——
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In Vivo——
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Synonyms——
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PathwayCell Cycle/DNA Damage
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TargetDNA/RNA Synthesis
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RecptorDNA/RNA Synthesis
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Research Area——
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Indication——
Chemical Information
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CAS Number168427-74-5
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Formula Weight325.32
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Molecular FormulaC13H19N5O5
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Purity>98% (HPLC)
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SolubilityIn Vitro:?DMSO : 50 mg/mL (153.69 mM; Ultrasonic )
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SMILESCOCCO[C@@H]1[C@H](O)[C@@H](CO)O[C@H]1N1C=NC2=C(N)N=CN=C12
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
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Capecitabine
Prodrug of 5-Fluorouracil (5-FU). Selectively activated in tumor cells by thymidine phosphorylase; inhibits DNA synthesis upon conversion to 5-FU. Orally available.
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NSAH?
NSAH is a nonnucleoside inhibitor of human ribonucleotide reductase (hRR).with cell-free IC50 of 32 μM and cell-based IC50 of ~250 nM, respectively.A unique nonnucleoside small-molecule hRR inhibitor, naphthyl salicylic acyl hydrazone (NSAH), using virtual screening, binding affinity, inhibition, and cell toxicity assays.?NSAH binds to hRRM1 with an apparent dissociation constant of 37 μM, and steady-state kinetics reveal a competitive mode of inhibition.?
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SR15006
SR15006 is Krüppel-like factor 5 (KLF5) inhibitor (IC50 = 41.6 nM).
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