Corr4A

CAS No. 421580-53-2

Corr4A( Corr 4A )

Catalog No. M14435 CAS No. 421580-53-2

A small molecule corrector of ΔF508-CFTR with IC50 of 6.0 uM.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
5MG 459 In Stock
10MG 657 In Stock
25MG 1026 In Stock
50MG 1386 In Stock
100MG 1832 In Stock
200MG Get Quote In Stock
500MG 3655 In Stock
1G Get Quote In Stock

Biological Information

  • Product Name
    Corr4A
  • Note
    Research use only, not for human use.
  • Brief Description
    A small molecule corrector of ΔF508-CFTR with IC50 of 6.0 uM.
  • Description
    A small molecule corrector of ΔF508-CFTR with IC50 of 6.0 uM.
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    Corr 4A
  • Pathway
    Apoptosis
  • Target
    CFTR
  • Recptor
    CFTR
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    421580-53-2
  • Formula Weight
    456.963
  • Molecular Formula
    C21H17ClN4O2S2
  • Purity
    >98% (HPLC)
  • Solubility
    ——
  • SMILES
    CC1=C(C2=CSC(NC3=CC(Cl)=CC=C3OC)=N2)SC(NC(C4=CC=CC=C4)=O)=N1
  • Chemical Name
    N-[2-(5-chloro-2-methoxy-phenylamino)-4'-methyl-[4,5']bithiazolyl-2'-yl]-benzamide

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Boinot C, et al. J Pharmacol Exp Ther. 2014 Sep;350(3):624-34. 2. Talebian L, et al. Cell Physiol Biochem. 2009;23(1-3):199-204. 3. Coffman KC, et al. J Med Chem. 2014 Aug 14;57(15):6729-38. 4. Pedemonte N, et al. Mol Pharmacol. 2005 Dec;68(6):1736-46.
molnova catalog
related products
  • Olacaftor

    Olacaftor (VX-440, VX440) is a next-generation CFTR corrector, shows the potential to enhance the amount of CFTR protein at the cell’s surface and for treatment of cystic fibrosis.

  • BPO-27 racemate

    BPO-27 is a potent, metabolically stable CFTR inhibitor (IC50= 8 nM).

  • Bamocaftor

    Bamocaftor is a CFTR channel (DeltaF508-CFTR mutation) corrector for CF transmembrane conductance regulators designed to restore F508del-CFTR protein function.