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Olacaftor
CAS No. 1897384-89-2
Olacaftor( VX-440 | VX440 )
Catalog No. M12980 CAS No. 1897384-89-2
Olacaftor (VX-440, VX440) is a next-generation CFTR corrector, shows the potential to enhance the amount of CFTR protein at the cell’s surface and for treatment of cystic fibrosis.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 5MG | 672 | In Stock |
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| 50MG | 1962 | In Stock |
|
| 100MG | 2520 | In Stock |
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| 200MG | Get Quote | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
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Product NameOlacaftor
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NoteResearch use only, not for human use.
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Brief DescriptionOlacaftor (VX-440, VX440) is a next-generation CFTR corrector, shows the potential to enhance the amount of CFTR protein at the cell’s surface and for treatment of cystic fibrosis.
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DescriptionOlacaftor (VX-440, VX440) is a next-generation CFTR corrector, shows the potential to enhance the amount of CFTR protein at the cell’s surface and for treatment of cystic fibrosis.Fibrosis Phase 2 Clinical.
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In Vitro——
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In Vivo——
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SynonymsVX-440 | VX440
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PathwayApoptosis
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TargetCFTR
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RecptorCFTR
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Research AreaOther Indications
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IndicationFibrosis
Chemical Information
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CAS Number1897384-89-2
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Formula Weight539.666
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Molecular FormulaC29H34FN3O4S
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Purity>98% (HPLC)
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SolubilityIn Vitro:?DMSO : 50 mg/mL (92.65 mM)
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SMILESO=C(C1=CC=C(C2=CC(OCC(C)C)=CC(F)=C2)N=C1N3C(C)(C)C[C@H](C)C3)NS(=O)(C4=CC=CC=C4)=O
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Chemical NameN-(benzenesulfonyl)-6-[3-fluoro-5-(2-methylpropoxy)phenyl]-2-[(4S)-2,2,4-trimethylpyrrolidin-1-yl]pyridine-3-carboxamide
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
molnova catalog
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Ivacaftor
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(R)-BPO-27
(R)-BPO-27, the R enantiomer of BPO-27, CFTR chloride conductance with IC50 of 4 nM; BPO-27 S enantiomer is inactive.
