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Bamocaftor
CAS No. 2204245-48-5
Bamocaftor( —— )
Catalog No. M34520 CAS No. 2204245-48-5
Bamocaftor is a CFTR channel (DeltaF508-CFTR mutation) corrector for CF transmembrane conductance regulators designed to restore F508del-CFTR protein function.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 2MG | 565 | Get Quote |
|
| 5MG | 847 | Get Quote |
|
| 10MG | 1159 | Get Quote |
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| 25MG | 1647 | Get Quote |
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| 50MG | 2236 | Get Quote |
|
| 100MG | 2952 | Get Quote |
|
| 500MG | Get Quote | Get Quote |
|
| 1G | Get Quote | Get Quote |
|
Biological Information
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Product NameBamocaftor
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NoteResearch use only, not for human use.
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Brief DescriptionBamocaftor is a CFTR channel (DeltaF508-CFTR mutation) corrector for CF transmembrane conductance regulators designed to restore F508del-CFTR protein function.
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DescriptionBamocaftor (VX-659) is a cystic fibrosis transmembrane conductance regulator (CFTR) corrector designed to restore F508del-CFTR protein function. Bamocaftor can be used combine with Tezacaftor (HY-15448) and Ivacaftor (HY-13017) in cystic fibrosis research.
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In VitroBamocaftor is a CFTR corrector designed to restore F508del-CFTR protein function.
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In Vivo——
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Synonyms——
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PathwayApoptosis
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TargetCFTR
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RecptorCFTR
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Research Area——
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Indication——
Chemical Information
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CAS Number2204245-48-5
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Formula Weight591.65
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Molecular FormulaC28H32F3N5O4S
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Purity>98% (HPLC)
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SolubilityIn Vitro:?DMSO : 100 mg/mL (169.02 mM; Ultrasonic (<60°C)
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SMILESC[C@@H]1CN(c2nc(ccc2C(=O)NS(=O)(=O)c2ccccc2)-n2ccc(OCCC3(CC3)C(F)(F)F)n2)C(C)(C)C1
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Ghelani DP, et al. Emerging Cystic Fibrosis Transmembrane Conductance Regulator Modulators as New Drugs for Cystic Fibrosis: A Portrait of in Vitro Pharmacology and Clinical Translation.?
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