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Disopyramide
CAS No. 3737-09-5
Disopyramide( —— )
Catalog No. M14291 CAS No. 3737-09-5
A class I anti-arrhythmic agent (one that interferes directly with the depolarization of the cardiac membrane and thus serves as a membrane-stabilizing agent) with a depressant action on the heart similar to that of guanidine.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 1 mL x 10 mM in DMSO | 28 | In Stock |
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| 10MG | 30 | In Stock |
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| 25MG | 48 | In Stock |
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| 50MG | 75 | In Stock |
|
| 100MG | 125 | In Stock |
|
| 200MG | 165 | In Stock |
|
| 500MG | Get Quote | In Stock |
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| 1G | Get Quote | In Stock |
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Biological Information
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Product NameDisopyramide
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NoteResearch use only, not for human use.
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Brief DescriptionA class I anti-arrhythmic agent (one that interferes directly with the depolarization of the cardiac membrane and thus serves as a membrane-stabilizing agent) with a depressant action on the heart similar to that of guanidine.
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DescriptionA class I anti-arrhythmic agent (one that interferes directly with the depolarization of the cardiac membrane and thus serves as a membrane-stabilizing agent) with a depressant action on the heart similar to that of guanidine. It also possesses some anticholinergic and local anesthetic properties. (In Vitro):HERG tail currents recorded at -40 mV following test pulses to +30 mV were inhibited in a dose-dependent fashion by Disopyramide concentrations within the clinical range (IC50=7.23 μM).
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In VitroHERG tail currents recorded at -40 mV following test pulses to +30 mV were inhibited in a dose-dependent fashion by Disopyramide concentrations within the clinical range (IC50=7.23 μM).
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In Vivo——
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Synonyms——
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PathwayEndocrinology/Hormones
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TargetAChR
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RecptormAChR| Potassium Channel| Sodium Channel
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Research Area——
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Indication——
Chemical Information
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CAS Number3737-09-5
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Formula Weight339.47
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Molecular FormulaC21H29N3O
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Purity>98% (HPLC)
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SolubilityWater: 44.9 mg/L
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SMILESO=C(N)C(C1=CC=CC=C1)(CCN(C(C)C)C(C)C)C2=CC=CC=N2
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1.Sugao M, et al. J Cardiovasc Pharmacol. 2005 Jun;45(6):545-9.
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