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Carnosic acid
CAS No. 3650-09-7
Carnosic acid( Carnosate )
Catalog No. M14256 CAS No. 3650-09-7
Carnosic acid (Carnosate) is a naturally occurring phenolic compound with antioxidant, anti-inflammatory and antimicrobial properties.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 10MG | 37 | In Stock |
|
| 50MG | 113 | In Stock |
|
| 100MG | 167 | In Stock |
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| 200MG | Get Quote | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
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Product NameCarnosic acid
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NoteResearch use only, not for human use.
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Brief DescriptionCarnosic acid (Carnosate) is a naturally occurring phenolic compound with antioxidant, anti-inflammatory and antimicrobial properties.
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DescriptionCarnosic acid (Carnosate) is a naturally occurring phenolic compound with antioxidant, anti-inflammatory and antimicrobial properties, inhibits the BCL9/β-catenin interaction with Ki of 3.3 uM; inhibits β-catenin-dependent transcription, and destabilizes oncogenic β-catenin in colon cancer cells; reduces the expression of Sox2 and the number of SOX2+ cells in MB sphere cultures.
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In Vitro——
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In Vivo——
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SynonymsCarnosate
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PathwayWnt/Notch/Hedgehog
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TargetBeta-catenin
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RecptorROS
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Research AreaCancer
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Indication——
Chemical Information
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CAS Number3650-09-7
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Formula Weight332.4
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Molecular FormulaC20H28O4
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Purity>98% (HPLC)
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SolubilityDMSO: 100 mg/mL, 300.82 mM; Water: Insoluble （ < 1 mg/ml refers to the product slightly soluble or insoluble )
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SMILESO=C([C@]12CCCC(C)(C)[C@]1([H])CCC3=C2C(O)=C(O)C(C(C)C)=C3)O
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Chemical Name4a(2H)-Phenanthrenecarboxylic acid, 1,3,4,9,10,10a-hexahydro-5,6-dihydroxy-1,1-dimethyl-7-(1-methylethyl)-, (4aR-trans)-
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Rodriguez-Blanco J, et al. Oncogene. 2017 Jul 17. doi: 10.1038/onc.2017.232.
2. de la Roche M, et al. Nat Commun. 2012 Feb 21;3:680.
3. de la Roche M, et al. Cancer Res. 2014 Mar 1;74(5):1495-505.
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