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T-155535
CAS No. 925001-05-4
T-155535( T155535 )
Catalog No. M16627 CAS No. 925001-05-4
T-155535 is a small molecule inhibitor that effectively inhibits the β-catenin/Tcf4 interaction with Ki of 21 uM in AlphaScreen assay.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
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Biological Information
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Product NameT-155535
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NoteResearch use only, not for human use.
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Brief DescriptionT-155535 is a small molecule inhibitor that effectively inhibits the β-catenin/Tcf4 interaction with Ki of 21 uM in AlphaScreen assay.
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DescriptionT-155535 is a small molecule inhibitor that effectively inhibits the β-catenin/Tcf4 interaction with Ki of 21 uM in AlphaScreen assay; displays 2.8-fold and 5.2-fold selectivity over β-catenin/E-cadherin and β-catenin/APC interactions, respectively.
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In Vitro——
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In Vivo——
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SynonymsT155535
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PathwayWnt/Notch/Hedgehog
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TargetBeta-catenin
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RecptorBeta-catenin
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Research Area——
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Indication——
Chemical Information
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CAS Number925001-05-4
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Formula Weight315.709
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Molecular FormulaC16H10ClNO4
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Purity>98% (HPLC)
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Solubility——
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SMILESC1=CC(=CC=C1C2=CC(=NO2)C(=O)O)OC3=CC=C(C=C3)Cl
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Chemical Name5-(4-(4-chlorophenoxy)phenyl)isoxazole-3-carboxylic acid
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Zhang M, et al. ACS Med Chem Lett. 2013 Jan 8;4(2):306-11.
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