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MIN-101
CAS No. 359625-79-9
MIN-101( Roluperidone | CYR-101 | MT-210 | MIN101 )
Catalog No. M14236 CAS No. 359625-79-9
MIN-101 (Roluperidone, CYR-101, MT-210) is a higly potent 5-HT2A and sigma 2 receptor antagonist.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 2MG | 29 | In Stock |
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| 5MG | 45 | In Stock |
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| 10MG | 75 | In Stock |
|
| 25MG | 150 | In Stock |
|
| 50MG | 239 | In Stock |
|
| 100MG | 367 | In Stock |
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| 200MG | Get Quote | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
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Product NameMIN-101
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NoteResearch use only, not for human use.
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Brief DescriptionMIN-101 (Roluperidone, CYR-101, MT-210) is a higly potent 5-HT2A and sigma 2 receptor antagonist.
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DescriptionMIN-101 (Roluperidone, CYR-101, MT-210) is a higly potent 5-HT2A and sigma 2 receptor antagonist, with no direct dopamine affinities, for treatment of negative symptoms in schizophrenia.Schizophrenia Phase 3 Clinical.
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In VitroRoluperidone (CYR-101) also shows binding affinity for α1-adrenergic receptors but low or no affinity for muscarinic, cholinergic, and histaminergic receptors. Although Roluperidone (CYR-101) has no affinities for pre- or postsynaptic dopaminergic receptors, it is probable that sigma-2 receptors are implicated in the modulation of dopamineand glutamatergic pathways, as well as in calcium neuronal modulation.
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In Vivo——
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SynonymsRoluperidone | CYR-101 | MT-210 | MIN101
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PathwayAutophagy
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TargetSigma receptor
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RecptorSigma Receptor
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Research AreaNeurological Disease
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IndicationSchizophrenia
Chemical Information
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CAS Number359625-79-9
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Formula Weight366.429
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Molecular FormulaC22H23F2N2O2
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Purity>98% (HPLC)
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SolubilityDMSO : 33.33 mg/mL 90.96 mM;H2O : < 0.1 mg/mL
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SMILESO=C1N(CC2CCN(CC(C3=CC=C(F)C=C3)=O)CC2)CC4=C1C=CC=C4
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Chemical Name2-[[1-[2-(4-Fluorophenyl)-2-oxoethyl]-4-piperidinyl]methyl]-2,3-dihydro-1H-isoindol-1-one
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Davidson M, et al. Am J Psychiatry. 2017 Dec 1;174(12):1195-1202.
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