Cart
sales@molnova.com
Home - Products - Autophagy - Sigma receptor - MIN-101

MIN-101

CAS No. 359625-79-9

MIN-101( Roluperidone | CYR-101 | MT-210 | MIN101 )

Catalog No. M14236 CAS No. 359625-79-9

MIN-101 (Roluperidone, CYR-101, MT-210) is a higly potent 5-HT2A and sigma 2 receptor antagonist.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
5MG 87 Get Quote
10MG 140 Get Quote
25MG 250 Get Quote
50MG 410 Get Quote
100MG 605 Get Quote
200MG Get Quote Get Quote
500MG Get Quote Get Quote
1G Get Quote Get Quote
Get Quotation Bulk Inquiry Add to Cart

Biological Information

  • Product Name
    MIN-101
  • Note
    Research use only, not for human use.
  • Brief Description
    MIN-101 (Roluperidone, CYR-101, MT-210) is a higly potent 5-HT2A and sigma 2 receptor antagonist.
  • Description
    MIN-101 (Roluperidone, CYR-101, MT-210) is a higly potent 5-HT2A and sigma 2 receptor antagonist, with no direct dopamine affinities, for treatment of negative symptoms in schizophrenia.Schizophrenia Phase 3 Clinical.
  • In Vitro
    Roluperidone (CYR-101) also shows binding affinity for α1-adrenergic receptors but low or no affinity for muscarinic, cholinergic, and histaminergic receptors. Although Roluperidone (CYR-101) has no affinities for pre- or postsynaptic dopaminergic receptors, it is probable that sigma-2 receptors are implicated in the modulation of dopamineand glutamatergic pathways, as well as in calcium neuronal modulation.
  • In Vivo
    ——
  • Synonyms
    Roluperidone | CYR-101 | MT-210 | MIN101
  • Pathway
    Autophagy
  • Target
    Sigma receptor
  • Recptor
    Sigma Receptor
  • Research Area
    Neurological Disease
  • Indication
    Schizophrenia

Chemical Information

  • CAS Number
    359625-79-9
  • Formula Weight
    366.429
  • Molecular Formula
    C22H23F2N2O2
  • Purity
    >98% (HPLC)
  • Solubility
    DMSO : 33.33 mg/mL 90.96 mM;H2O : < 0.1 mg/mL
  • SMILES
    O=C1N(CC2CCN(CC(C3=CC=C(F)C=C3)=O)CC2)CC4=C1C=CC=C4
  • Chemical Name
    2-[[1-[2-(4-Fluorophenyl)-2-oxoethyl]-4-piperidinyl]methyl]-2,3-dihydro-1H-isoindol-1-one

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Davidson M, et al. Am J Psychiatry. 2017 Dec 1;174(12):1195-1202.
Calculator

Molecular Weight Calculator

Dilution Calculator

Molarity Calculator

molnova catalog
related products

  • KB-5492 free base

    KB-5492 free base is an orally available and selective antiulcer agent that inhibits sigma receptors, inhibits [3H]1,3-di(2-tolyl)guanidine (DTG) binding to sigma receptors, and may be useful in the study of gastric lesions and gastric secretion.

  • S1RA

    A potent and selective sigma-1 receptor antagonist with Ki of 17 nM; shows excellent selectivity over sigma-2 receptor (Ki>1 uM).

  • Opipramol

    Opipramol (Ensidon) is a compound with antidepressant activity that attenuates cocaine-seeking behavior in a rat model of self-administration.

Sign In Join Free