BMS-394136( BMS394136 )

Catalog No. M14168 CAS No. 343246-73-1

BMS-394136 is a potent, selective IKur/Kv1.5inhibitor.

Purity : >98% (HPLC)

COA

Datasheet

HNMR

HPLC

MSDS

Handing Instructions

Size	Price / USD	Stock	Quantity
5MG	614	In Stock
10MG	873	In Stock
25MG	1311	In Stock
50MG	1730	In Stock
100MG	2316	In Stock
200MG	Get Quote	In Stock
500MG	4585	In Stock
1G	Get Quote	In Stock

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Biological Information

Product Name

BMS-394136
Note

Research use only, not for human use.
Brief Description

BMS-394136 is a potent, selective IKur/Kv1.5inhibitor.
Description

BMS-394136 is a potent, selective IKur/Kv1.5inhibitor, increases atrial action potential duration (APD) and prolongs AERP but not VERP in both rabbits and beagles.Heart Arrhythmia Phase 1 Discontinued.
In Vitro

——
In Vivo

——
Synonyms

BMS394136
Pathway

Cell Cycle/DNA Damage
Target

Potassium Channel
Recptor

Potassium Channel
Research Area

Cardiovascular Disease
Indication

Heart Arrhythmia

Chemical Information

CAS Number

343246-73-1
Formula Weight

471.357
Molecular Formula

C24H21Cl2FN4O
Purity

>98% (HPLC)
Solubility

——
SMILES

CC1=C([C@H](n2c(ccn2)N1)c3ccc(c(c3)Cl)Cl)C(=O)N4CCC[C@H]4c5ccc(cc5)F
Chemical Name

Pyrrolidine, 1-[[(7R)-7-(3,4-dichlorophenyl)-4,7-dihydro-5-methylpyrazolo[1,5-a]pyrimidin-6-yl]carbonyl]-2-(4-fluorophenyl)-, (2S)- (9CI)

Shipping & Storage Information

Storage

(-20℃)
Shipping

With Ice Pack
Stability

≥ 2 years

Reference

1. Dezhi Xing, et al. Abstract 2515: A Selective IKur Blocker, BMS-394136 Selectively Prolongs Atrial APD and Refractoriness in Beagles and Rabbits. Circulation. 2009;120:S654.

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